Recent Advances in Non-Precious Metal Catalysis

Abstract

This review provides a summary of recently published developments in the field of nonprecious metal catalysis (NPMC) and highlights the range of synthetic applications captured in published research between July and October 2021. This review is an installment of the review series on this research area briefing developments and highlights on the synthetic applications of Ni, Cu, Fe, and Co catalysis. There has been an evident increase in publications in NPMC, which indicates widespread interest among the research laboratories in academia and industry in the development and utilization of the catalytic applications of these metals.

Chemoenzymatic Cascades Combining Biocatalysis and Transition Metal Catalysis for Asymmetric Synthesis

“…On the other hand, the versatility of Cu, Ni, Rh, Pt and Co opens new possibilities in chemoenzymatic cascades. This is especially attractive when non‐precious metals are considered, [90] where Ni catalysis will have a prominent role in the next years.…”

The E factor at 30: a passion for pollution prevention

“…Pd. Pt, Rh and Ru, with non-precious metal catalysts (NPMCs), 9 particularly Fe, Cu and Ni, otherwise known as Earth abundant metals (EAMs) 10 as sustainable, cost-effective alternatives. It is worth noting, in this context, that these are the very same elements contained in the active sites of enzymes catalysing a variety of redox processes in nature.…”

Collaboration as a Key to Advance Capabilities for Earth-Abundant Metal Catalysis

“…In addition, we have established highly productive collaborations with two leading academic research groups in the field of EAM catalysis, Prof. Keary Engle's group at the Scripps Research Institute and Prof. Paul Chirik's group at Princeton University. Finally, though BMS is not a participating company, we would like to acknowledge the impactful collaborative work that is being done by the precompetitive alliance for nonprecious metal catalysis at AbbVie, Boehringer Ingelheim, and Pfizer, 15 which has led to a number of advances in the field of EAM catalysis and has inspired and influenced many of our own efforts in this area.…”