Recent advances in nanotechnology for simultaneous detection of multiple pathogenic bacteria

DNA self-assembled Au nanoparticle clusters on silver nanorod arrays for high-sensitive and multiplex detection of cancer-related biomarkers

“…† The results show that the F-AgNR SERS sensors are highly uniform, the SERS signal variations for all three SERS tags are less than 9%, and 6 batches of AgNR substrates only produce <8.3% variation in different detection signals, i.e., the sensors are highly reproducible. Therefore, based on the above results, the following four conclusions can be drawn: (1) The designed F-AgNR SERS sensor is only specific to biomarkers of miR-21, miR-486, and CEA; (2) The sensor can achieve single, dual and triple biomarker detections; (3) With the same concentration of the biomarker, the SERS intensity of the SERS tag peak with respect to the corresponding biomarker increases significantly when the detection changes from single to dual, and then to triple biomarker detection; and (4) The sensors are very uniform and highly reproducible.…”

“…Many different techniques have been developed to target this goal. 1,2 Among them, surfaceenhanced Raman spectroscopy (SERS), with the potential to achieve single molecule detection, is very attractive and promising for multiplex detection. 3,4 SERS offers a unique "signature" spectral profile with very narrow spectral peaks for an individual analyte, and has been demonstrated to be able to detect trace amounts of biomarkers.…”

Construction of Nanocarriers Based on Endogenous Cell Membrane and Their Application in Nanomedicine

“…It also plays an important role in the immune response, cancer development and other normal physiological processes, and has the advantages of stability, biocompatibility, low immunogenicity, low toxicity and biological barrier permeability. [ 43‐44 ]…”

Engineering of Portable Smartphone Integrated with Liposome‐Encapsulated Curcumin for Onsite Visual Ratiometric Fluorescence Imaging of Hypochlorite

“…Apart from these, some groups have also contributed to developing portable smartphone‐based ratiometric fluorescence sensors for onsite detection of ClO − [8] . Although acceptable detection limits have been obtained by these fluorescence assays, they often suffer from the drawbacks of complicated multistep synthesis and nonspecific binding in real samples, leading to potential false positive readouts [9] . Therefore, it is still very desirable to develop a simple and efficient analytical platform to overcome these issues above for realizing onsite ratiometric fluorescent monitoring of ClO − , particularly in the heavy use of it to block the epidemic of COVID‐19 today.…”