Recent Advances in Metal‐Catalyzed Bond‐Forming Reactions of Ketene S,S‐Acetals

Abstract

Scheme 6. CuBr 2 /BF 3 ·OEt 2 -co-catalyzed [3+ +2] cyclizations of 1 and 8/10. Scheme7.CuBr 2 -catalyzed reaction of 1 and 13. Scheme8.CuBr 2 -catalyzed reaction of 1 and 15. Scheme 19. AlCl 3 -catalyzed multicomponentr eactionsb ased on a-benzoyl ketened imethyl thioacetal. Scheme20. FeCl 3 -catalyzed cross-coupling of 1 and 44. Scheme 30. Cu(OH) 2 -catalyzed a-trifluoromethylation of 1. Scheme 31. Cu(OH) 2 -catalyzed a-alkoxylationof1. Scheme 32. CuI-catalyzed a-thiomethylation of 1. Scheme33. CuCl-catalyzed a-azidation of 1. Scheme 43. Pd-catalyzedd esulfurative cross-coupling and cyclization of 71 and 90. Scheme 44. FeCl 3 -catalyzedd esulfurative indolizationo f74.

Trimetallic Oxide Electrocatalyst for Enhanced Redox Activity in Zinc–Air Batteries Evaluated by In Situ Analysis

“…[ 34 ] After the addition of Mo atom in the NCMO@rGO catalyst, strong crystalline peaks appeared at 36.1⁰ (100) on the key crystal plane, respectively (JCPDS: 050–0739). [ 35 ] These results demonstrate the successful conversion of spinel to a trimetallic catalyst.…”

Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals

“…Ketene dithioacetals have widespread use in organic chemistry, serving as important building blocks for obtaining heterocyclic scaffolds using various methods (Huang et al., 2020; Xu et al., 2019). These compounds are traditionally prepared through reactions consisting of: (i) deprotonation of hydrogen‐active compounds, (ii) addition to carbon disulfide, and (iii) methylation of the resulting sulfide anions (Thomae et al., 2009).…”

Borane‐Catalyzed, HFIP‐Assisted Carbene Insertion into Internal Alkenyl C−H Bonds under Metal‐Free Conditions

“…[14] DFT calculations and experimental studies have revealed that Lewis acid B(C 6 F 5 ) 3 either facilitates carbene generation from donor-acceptor diazo compounds or promote carbenium ion generation for autocatalytic pyrazole formation. [16] During the continuous investigation of alkenyl CÀ H functionalization, [17,18] we envisioned that a combination of Lewis acid B(C 6 F 5 ) 3 as the catalyst and HFIP as the mediator might be applied in carbene insertion into CÀ H bonds of internal alkenes, that is, α-oxo ketene dithioacetals, under metal-free conditions, which will be a supplement to transition-metalcatalyzed carbene insertion into alkenyl CÀ H bonds. Herein, we disclose B(C 6 F 5 ) 3 -catalyzed, HFIP-mediated carbene insertion into α-alkenyl CÀ H bonds of αoxo ketene dithioacetals, a class of polarized internal alkenes (Scheme 1c).…”