Recent Advances in Iron Catalyzed Oxidation Reactions of Organic Compounds

Abstract

Iron-catalyzed oxidation reactions have been increasingly investigated in the past two decades and have seen a major increase in research activity. This review article demonstrates the vigorous research activities in the field based on examples from the most recent literature. Catalyst systems are discussed that are active in the oxygenation of alkanes and alkenes to obtain alcohols, ketones or epoxides. Iron-catalyzed oxidation of alcohols to the corresponding carbonyl units are also included. Enantioselective and heterogeneous catalyst systems are presented as well, and a brief overview of mechanistic pictures is given. B. Bauer was born in Nuremberg, Germany. He received PhD degree in 2003 from the University of Erlangen-Nuremberg; under the supervision of Prof. John A. Gladysz, he performed ring closing metathesis reactions in the coordination sphere of transition metals to obtain macrocyclic metal complexes. He performed postdoctoral research at the University of California, Riverside with Keith Hollis, working on rhodium and iridium carbene complexes with catalytic activity in hydroamination and hydrosilylation reactions. In 2005 he joined Illinois Wesleyan University for one year as a Visiting Assistant Professor. In 2006 he joined the University of Missouri -St. Louis as an Assistant Professor, and became promoted to Associate Professor in 2012. His research interests are the synthesis and characterization of ruthenium and iron complexes to be employed in catalytic processes. His work on ruthenium mainly concerns the catalytic activation of propargylic alcohols and their derivatives toward nucleophilic substitution reactions. In the area of iron catalysis, he published a number of iron complexes to be catalytically active in the oxidation of hydrocarbons and alcohols.

Oil-Dispersed α-Fe2O3 Nanoparticles as a Catalyst for Improving Heavy Oil Oxidation

“…Iron-based catalysts or co-catalysts are well-introduced and famous species for catalyzing oxidation reactions in organic chemistry. ,, Iron and other transition metals mainly catalyze oxidation through the redox property. ,− Iron oxide is one of the famous species and effective catalysts for the oxidation reactions of organic compounds such as alcohols, , alkenes, , asphaltenes, ,, and crude oils. , In addition, iron oxides can be easily applied in industry because of their relatively low cost. Therefore, in this work, we focus on iron oxide (Fe 2 O 3 ).…”

Reinvestigating FeBr3-Catalyzed Alcohol Oxidation with H2O2: Is a High-Valent Iron Species (HIS) or a Reactive Brominating Species (RBS) Responsible for Alcohol Oxidation?

“…These results revealed that the anionic ligand of iron had a crucial effect on the alcohol oxidation. In the case of [NO 3 – ] and [Cl – ], we suspected that in situ generation of NO x and hypochlorous acid was responsible for the menthol oxidation . Nevertheless, this finding suggested that the FeBr 3 /H 2 O 2 system was less likely to involve the high-valent iron species for the alcohol oxidation (entries 9 and 10).…”

Clean Catalytic Oxidation for Derivatization of Key Biobased Platform Chemicals: Ethanol, Glycerol, and Hydroxymethyl Furfural

“…The alternative of employing iron-based catalysts and hydrogen peroxide as oxidant is gaining importance for the liquid phase oxidation of glycerol under mild conditions (base-free, ambient temperature, and atmospheric pressure). , Crotti and Farnetti performed the glycerol oxidation in an acetonitrile/water mixture using homogeneous iron complexes associated to the tridentate ligand bis­(2-pyridinylmethyl)­amine (BPA) as catalyst. They reported that high selectivity toward DHA or formic acid could be achieved by tuning operating conditions.…”