Recent Advances in Hydrophobic Deep Eutectic Solvents for Extraction

Dwamena, Amos K.

doi:10.3390/separations6010009

Cited by 184 publications

(100 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Terpene-based hydrophobic eutectic solvents were proposed as extractants for metals, biomolecules, phytocannabinoids, lower alcohols, polycyclic aromatic hydrocarbons, and pesticides. 17 In a mixture, the decrease of the melting point without the formation of a new compound is a feature that increases the number of potential substances that can be used as solvents. This allows the use of terpenes with high melting points since the mixture melting temperature can be tailored with a second component.…”

Section: ■ Introductionmentioning

confidence: 99%

Greener Terpene–Terpene Eutectic Mixtures as Hydrophobic Solvents

Martins

Silva

Schaeffer

et al. 2019

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

Natural products can be the basis for the development of green solvents, relevant for the advancement of new, more sustainable processes and products. In this work, 10 binary mixtures constituted by terpenes are prepared and characterized. Their solid−liquid phase diagrams show that room-temperature solvents can be prepared from solid terpenes in a wide composition range. These diagrams are accurately described by the conductor-like screening model for real solvents, showing it to be a useful predictive tool for the design of novel natural solvents. At the eutectic point, these mixtures possess low viscosities, densities lower than water, and high boiling temperatures. The low water solubility in the eutectic solvents together with its negligible impact on the properties measured is a strong indicator of the hydrophobic character of these mixtures. The tunable character of these mixtures is demonstrated by studying the solvatochromic parameters in the entire concentration region, the properties of the final solvents being tuned by simply varying the mole fraction of the terpenes. The high potential of this tunable character is shown in the selective extraction of dyes from their aqueous solutions. This work is expected to devise new insights concerning these solvents as well as to boost their application in green industrial processes.

show abstract

Section: ■ Introductionmentioning

confidence: 99%

Greener Terpene–Terpene Eutectic Mixtures as Hydrophobic Solvents

Martins

Silva

Schaeffer

et al. 2019

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

show abstract

“…A deep eutectic solvent is composed of, at least, an hydrogen bond acceptor (HBA) and an hydrogen bond donor (HBD) species, that form a eutectic mixture deviating from ideality, thus presenting a significant decrease on the melting temperature [31]. DES, if properly designed, may be considered as low-cost based solvents, and have been identified as promising environmental-friendly alternatives in extraction and conversion processes [32][33][34], preparation of innovative materials [35,36], and extraction of high-value compounds and fractionation of biomass [37][38][39][40]. A large number of stable DES based on natural compounds, such as organic acids, amino acids and sugars, called natural deep eutectic solvents (NADES), have also been recently described [41].…”

Section: Introductionmentioning

confidence: 99%

Extraction of High Value Triterpenic Acids from Eucalyptus globulus Biomass Using Hydrophobic Deep Eutectic Solvents

et al. 2020

View full text Add to dashboard Cite

Triterpenic acids (TTAs), known for their promising biological properties, can be found in different biomass sources and related by-products, such as Eucalyptus globulus bark, and have been extracted using organic volatile solvents such as dichloromethane. Recently, deep eutectic solvents (DES) have been identified as promising alternatives for the extraction of value-added compounds from biomass. In the present work, several hydrophobic DES were tested for the extraction of TTAs from E. globulus bark. Initial solubility studies revealed that DES based on menthol and thymol as the most promising solvents for these compounds given the highest solubilities obtained for ursolic acid (UA) at temperatures ranging from room temperature up to 90 °C. Accordingly, an eutectic mixture of menthol:thymol (1:2) was confirmed as the best candidate for the TTAs extraction from E. globulus outer bark, leading to extraction yields (weight of TTA per weight of biomass) at room temperature of 1.8 wt% for ursolic acid, 0.84 wt% for oleanolic acid and 0.30 wt% for betulinic acid. These values are significantly higher than those obtained with conventional organic solvents under similar conditions. The results obtained using these DES are promising for the recovery of TTAs for nutraceutical and pharmacological applications, while reinforcing the potential of DES as promising solvents to be applied in biorefinery processes.

show abstract

“…Secondly, the DESs have a large electrochemical window, which allows the application of electrochemical techniques such as electrodeposition to refine metals [36][37][38]. Thirdly, Tereshatov et al ( [39]) envisaged, for the first time, the possibility to use hydrophobic DESs ( [40]) for the solvent extraction of metal ions from aqueous solutions. This could constitute one step towards the design of cleaner solvent extraction processes since it would avoid the use of hydrocarbon diluents while using cheap chemicals and without needing any extracting molecule in most cases.…”

Section: Organic Phasementioning

confidence: 99%

Review on Hydrometallurgical Recovery of Metals with Deep Eutectic Solvents

Zante

Boltoeva

2020

Sustainable Chemistry

View full text Add to dashboard Cite

Deep eutectic solvents (DESs) appeared recently as a new class of green designer solvents. The recovery of metals using hydrometallurgy is of major importance with the growth in metal demand. Several authors used these solvents for the hydrometallurgical recovery of metals from primary and secondary resources, and these studies are reviewed in the present work. Hydrophilic DESs can be used for the leaching of metals and have great potential to replace mineral acids, and even to reduce water consumption. Efficient and selective leaching of metals from minerals or wastes is feasible by using DESs. However, the kinetics of leaching as well as the physicochemical properties of DESs are still limiting their large-scale application. Electrochemical recovery from DES is also possible but deserves further investigation. Finally, the recovery of metals from aqueous solutions using hydrophobic DESs was studied in several works. For the solvent extraction of metals, hydrophobic DESs constitute credible alternative ionic liquids.

show abstract

Recent Advances in Hydrophobic Deep Eutectic Solvents for Extraction

Cited by 184 publications

References 72 publications

Greener Terpene–Terpene Eutectic Mixtures as Hydrophobic Solvents

Greener Terpene–Terpene Eutectic Mixtures as Hydrophobic Solvents

Extraction of High Value Triterpenic Acids from Eucalyptus globulus Biomass Using Hydrophobic Deep Eutectic Solvents

Review on Hydrometallurgical Recovery of Metals with Deep Eutectic Solvents

Contact Info

Product

Resources

About