Recent advances in host-focused molecular tools for investigating host-gut microbiome interactions
Siyao Wang,
Xu Gong,
Fei Xiao
et al.
Abstract:Microbial communities in the human gut play a significant role in regulating host gene expression, influencing a variety of biological processes. To understand the molecular mechanisms underlying host-microbe interactions, tools that can dissect signaling networks are required. In this review, we discuss recent advances in molecular tools used to study this interplay, with a focus on those that explore how the microbiome regulates host gene expression. These tools include CRISPR-based whole-body genetic tools … Show more
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