Recent advances in endoscopic management of gastric neoplasms

Cheema, Hira; Tharian, Benjamin; Inamdar, Sumant; Garcia‐Saenz‐de‐Sicilia, Mauricio; Cengız, Cem

doi:10.4253/wjge.v15.i5.319

Cited by 4 publications

(1 citation statement)

References 137 publications

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“…For instance, in GEP NENs, gastric tumours represent rare forms originating from stomach neuroendocrine cells, which have lately been more often identified due to frequent routine investigations such as oesophagus-gastro-duodenoscopies [1,12]. In addition to typical grades of low, intermediate, and high, they are classified as type 1 and 2 (with gastrin overproduction in relation to atrophic gastritis and with a multiple endocrine neoplasia type 1 syndrome/Zollinger-Ellison syndrome due to a gastrinoma in type 2) as well as type 3 and 4 (sporadic forms with normal gastrin).…”

Section: Prognostic Markers and Multimodal Management Of Nensmentioning

confidence: 99%

Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches

Carsote,

Nistor

2024

Biomedicines

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Section: Prognostic Markers and Multimodal Management Of Nensmentioning

confidence: 99%

Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches

Carsote,

Nistor

2024

Biomedicines

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Unveiling clinicopathologic features and outcomes for endoscopic submucosal dissection of early gastric cancer at gastric angulus in China

Wu,

Li,

Cui

et al. 2024

BMC Cancer

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Background With advances in endoscopic submucosal dissection (ESD) technique, an increasing number of the Chinese population are being diagnosed with early gastric cancers (EGCs) at gastric angulus. However, the relationship between gastric angulus and EGCs remains obscure. Objectives We aimed to unveil the unreported location characteristics of gastric angulus in Chinese EGC patients and the correlation between the degree of submucosal fibrosis and ESD outcomes. Methods We retrospectively reviewed the medical records of EGC patients treated with ESD from January 2010 to March 2023. We retrospectively investigated and analyzed 740 EGC patients using multiple analyses. Results Following gastric antrum (53.1%), the gastric angulus (21.8%) emerged as the second-most prevalent site for EGCs. It had highest incidence of severe submucosal fibrosis and ulceration than the other parts. Multivariate analysis showed independent associations of submucosal fibrosis at the angulus with ulceration (OR: 3.714, 95% CI: 1.041–13.249), procedure duration (OR: 1.037, 95% CI: 1.014–1.061), and perforation complication (OR: 14.611, 95% CI: 1.626-131.277) (all P < 0.05). Conclusions The gastric angulus demonstrates the highest incidence of severe submucosal fibrosis and ulceration for EGCs identified by ESD. This condition is linked to unfavorable outcomes, typically increased perforation risks and prolonged operation duration. Therefore, meticulous dissection is crucial for patients with EGCs in the gastric angulus.

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Revolutionizing Gastrointestinal Disorder Management: Cutting-Edge Advances and Future Prospects

Suri,

Pande,

Sahu

et al. 2024

JCM

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In recent years, remarkable strides have been made in the management of gastrointestinal disorders, transforming the landscape of patient care and outcomes. This article explores the latest breakthroughs in the field, encompassing innovative diagnostic techniques, personalized treatment approaches, and novel therapeutic interventions. Additionally, this article emphasizes the use of precision medicine tailored to individual genetic and microbiome profiles, and the application of artificial intelligence in disease prediction and monitoring. This review highlights the dynamic progress in managing conditions such as inflammatory bowel disease, gastroesophageal reflux disease, irritable bowel syndrome, and gastrointestinal cancers. By delving into these advancements, we offer a glimpse into the promising future of gastroenterology, where multidisciplinary collaborations and cutting-edge technologies converge to provide more effective, patient-centric solutions for individuals grappling with gastrointestinal disorders.

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Recent advances in endoscopic management of gastric neoplasms

Cited by 4 publications

References 137 publications

Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches

Neuroendocrine Neoplasia: From Pathophysiology to Novel Therapeutic Approaches

Unveiling clinicopathologic features and outcomes for endoscopic submucosal dissection of early gastric cancer at gastric angulus in China

Revolutionizing Gastrointestinal Disorder Management: Cutting-Edge Advances and Future Prospects

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