Recent advances in DNA-based electrogenerated chemiluminescence biosensors

Abstract

Electrogenerated chemiluminescence (also called electrochemiluminescence and abbreviated ECL) has made a vigorous development in the fields from biological analysis to clinical diagnosis due to its outstanding advantages such as high...

Antioxidant Cascade Modulated Electrochemiluminescence by a Biomimetic Metal–Organic Framework with Dual Enzymatic Activity for Disease Marker Immunoassays

“…Electrochemiluminescence (ECL), also called electrogenerated chemiluminescence, represents a powerful tool for creating biomolecular analysis protocols with a variety of advantageous properties, including low background, high sensitivity, high accuracy, and precision. , In recent years, it is widely accepted that the development of more prominent ECL analysis strongly depends on the pioneering of novel luminophores, while the specific applications are controlled by advanced sensing strategies. , In this context, several novel strategies have been widely explored, including electron transfer (ET), resonance energy transfer (RET), surface plasmon resonance (SPR), coreactant acceleration, free radical scavenging, DNA-assisted amplification strategies, etc. − Uniquely, ECL analysis based on free radical scavenging, which has not been widely recruited, still has an extremely wide scope for development, whether based on companion facilities for new luminophores or new paradigm modifications of traditional luminophores. − Considering that the scalability of new luminescent materials still needs to be explored, identifying implementable solutions within the large operating space of conventional emitters is important for follow-up work.…”