Recent advances in diagnosis and treatment of gastrointestinal hemorrhage in infants and children

Hyams, Jeffrey S.; Leichtner, Alan M.; Schwartz, A

doi:10.1016/s0022-3476(85)80455-8

Cited by 29 publications

(8 citation statements)

References 76 publications

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“…The most direct and reliable way to detect bleeding source is upper GI endoscopy (9,12), especially if it is done within 24 h of bleeding (8,13). It is up to 90% effective in diagnosing infants who have peptic ulcer (3,13).…”

Section: Discussionmentioning

confidence: 99%

Fetal Gastric Ulcer Presenting with Bloody Amniotic Fluid

Wen,

Chen,

et al. 1992

J. pediatr. gastroenterol. nutr.

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Section: Discussionmentioning

confidence: 99%

Fetal Gastric Ulcer Presenting with Bloody Amniotic Fluid

Wen,

Chen,

et al. 1992

J. pediatr. gastroenterol. nutr.

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“…Shock is circulatory insufficiency, resulting in inadequate oxygen delivery that leads to global hypoperfusion and tissue hypoxia; in the context of GIB, shock is most likely to be hypovolemic (due to the inadequate circulating volume resulting from acute blood loss). Varices are abnormal distended veins, most frequently occurring in the esophagus (esophageal varices) and less frequently in the stomach (gastric varices) or other sites (ectopic varices), and usually occurring as a consequence of liver disease; variceal bleeding is characteristically severe and may be life-threatening[ 3 ]. Endoscopy is the visualization of the inside of the gastrointestinal tract accomplished by means of videoscope.…”

Section: Definitionsmentioning

confidence: 99%

Pediatric gastrointestinal bleeding: Perspectives from the Italian Society of Pediatric Gastroenterology

Romano

Oliva

Martellossi

et al. 2017

WJG

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There are many causes of gastrointestinal bleeding (GIB) in children, and this condition is not rare, having a reported incidence of 6.4%. Causes vary with age, but show considerable overlap; moreover, while many of the causes in the pediatric population are similar to those in adults, some lesions are unique to children. The diagnostic approach for pediatric GIB includes definition of the etiology, localization of the bleeding site and determination of the severity of bleeding; timely and accurate diagnosis is necessary to reduce morbidity and mortality. To assist medical care providers in the evaluation and management of children with GIB, the “Gastro-Ped Bleed Team” of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) carried out a systematic search on MEDLINE via PubMed () to identify all articles published in English from January 1990 to 2016; the following key words were used to conduct the electronic search: “upper GIB” and “pediatric” [all fields]; “lower GIB” and “pediatric” [all fields]; “obscure GIB” and “pediatric” [all fields]; “GIB” and “endoscopy” [all fields]; “GIB” and “therapy” [all fields]. The identified publications included articles describing randomized controlled trials, reviews, case reports, cohort studies, case-control studies and observational studies. References from the pertinent articles were also reviewed. This paper expresses a position statement of SIGENP that can have an immediate impact on clinical practice and for which sufficient evidence is not available in literature. The experts participating in this effort were selected according to their expertise and professional qualifications.

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“…In childhood 15% to 27% of gastrointestinal (GI) bleeding remains unexplained after conventional exploration (esogastroduodenoscopy, colonoscopy, small bowel barium follow-through, and/or enteral CT) (1,2). In these cases further investigation of the small bowel is necessary.…”

Section: Introductionmentioning

confidence: 99%