Recent advances in CoSalen-catalyzed radical reactions

Abstract

Recent advances in the iron-catalyzed CC bond formation via polar reactions of alcohols with carbon-centered nucleophiles Chinese Science Bulletin 57, 2335 (2012); N-heterocyclic carbene-catalyzed radical reactions SCIENCE CHINA Chemistry 63, 1 (2020); Recent advances in alkaline earth metal catalyzed hydroboration reactions SCIENTIA SINICA Chimica 50, 639 (2020); Advances of radical and photo reactions in natural products synthesis

Cobalt‐Catalyzed Oxytrifluoromethylation of N‐Allylamides toward Trifluoromethyl‐Containing Oxazolines

“…[15][16][17] Despite these impressive achievements, the development of novel green and sustainable synthesis of CF 3 -oxazolines is still demanding. [18] In continuance with our research interest [19][20][21][22] in the earthabundant, cost-effective cobalt catalysis, [23][24][25][26][27][28][29][30] we anticipate that the Co(salen) catalyst, with Togni's reagent II as the CF 3 source, should also effectively catalyze the oxytrifluoromethylation of N-allylamides for the efficient synthesis of CF 3 -containing oxazolines. Advantages of the current protocol includes the use of non-precious cobalt catalyst, easily prepared salen ligand, simple and mild reaction conditions.…”

Manganese/Enzyme Sequential Catalytic Pathway for the Production of Optically Active γ-Functionalized Alcohols

“…In recent years, the renaissance of metal–hydride chemistry has opened up a range of innovative olefin functionalization reactions founded on hydrogen atom transfer (HAT), including Drago–Mukaiyama hydration performed by Mn, Fe, or Co catalysts. Although these ground-breaking studies offer innovative pathways for alcohol synthesis, several unexplored issues persist, such as the influence of proximal functional groups on alkene hydration reactions and the integration of chemical and biocatalytic methods for the synthesis of optically active alcohols.…”

Aerobic C–C Bond Cleavage of Allylic Alcohols via Co-Catalyzed Hydrogen Atom Transfer

“…In the past few decades, metal hydride hydrogen atom transfer (MHAT) reactions have attracted more attention due to their high chemoselectivity and regioselectivity in alkene functionalization chemistry . The formation of C–C bonds via the HAT process has been well established, whereas the cleavage of C–C bonds was rare until Qin et al recently disclosed the first HAT-mediated C­(sp 3 )–C­(sp 2 ) bond cleavage of alkenes to access ketones .…”