Recent advances in composites based on cellulose derivatives for biomedical applications

Oprea, Madalina; Voicu, Ştefan Ioan

doi:10.1016/j.carbpol.2020.116683

Cited by 191 publications

(114 citation statements)

References 139 publications

Supporting

Mentioning

110

Contrasting

Unclassified

Order By: Relevance

“…Many literature review papers have been published on cellulose/ epoxy composites and chemical modification since it is a widespread reinforcement type in the composites field. Kumar and Kumari (2014) reviewed on processing and characterization of natural cellulose fibers/thermoset polymer composites, Agate, Joyce, Lucia, and Pal (2018) on cellulose/nanocellulose-based flexible-hybrid printed electronics, and conductive composites, Oprea and Voicu (2020) on recent advances in composites based on cellulose derivatives for biomedical applications, and, Sanjay et al (2019) on techniques for natural fibers as reinforcement in composites.…”

Section: Systematic Review and Methodologymentioning

confidence: 99%

Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review

Neves

Ornaghi

Zattera

et al. 2021

Carbohydrate Polymers

View full text Add to dashboard Cite

Cellulose and its derivatives are widely explored for films and thickening of pharmaceutical solutions, in paints, as reinforcement in composites, among others. This versatility is due to advantages such as renewability, low cost, and environmental friendliness. When used in polymer composites, due to the hydrophilic character of the cellulose, surface chemical modification is highly recommended to improve its compatibility with the polymeric matrix. Hence, this paper presents a systematic review of chemically modified cellulose/epoxy resin composites focusing on the last five years. The investigation followed the PRISMA protocol that delivers a meticulous summary of all available primary research in response to a research question. After including/excluding steps, thirty-six studies were included in the review. The results were presented focusing on thermal, mechanical and dynamic-mechanical properties of the composites. In brief, this methodology helped identifying the main gaps in knowledge in that field.

show abstract

Section: Systematic Review and Methodologymentioning

confidence: 99%

Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review

Neves

Ornaghi

Zattera

et al. 2021

Carbohydrate Polymers

View full text Add to dashboard Cite

show abstract

“…The cellulose produced by bacteria, including Komagataeibacter xylinus, seems to be a promising material [1,2]. Bacterial cellulose membrane (BC) is characterized by high purity (lack of lignin, hemicellulose, and pectin), high degree of polymerization, high porosity, beneficial mechanical properties, high crystallinity, good moldability, biocompatibility, good permeability, resistance to degradation, high water absorption capacity (more than 90% of its weight) and are environmentally friendly [3][4][5][6][7][8]. These properties, together with tensile strength, make these membranes applicable as a skin repair material [9] and in wound dressing [10,11].…”

Section: Introductionmentioning

confidence: 99%

“…In recent years gradually increasing demand for to use of "natural" products, perceived by patients as safer compared to products containing "synthetic" ingredients has been observed [12]. Furthermore, "green" polymers, are an environmentally friendly alternative to synthetic materials to reduce a large amount of non-biodegradable waste generated by industry [6].…”

Section: Introductionmentioning

confidence: 99%

Bacterial Cellulose Membrane Containing Epilobium angustifolium L. Extract as a Promising Material for the Topical Delivery of Antioxidants to the Skin

Nowak

Ossowicz‐Rupniewska

Rakoczy

et al. 2021

IJMS

View full text Add to dashboard Cite

Bacterial cellulose membranes (BCs) are becoming useful as a drug delivery system to the skin. However, there are very few reports on their application of plant substances to the skin. Komagataeibacter xylinus was used for the production of bacterial cellulose (BC). The BC containing 5% and 10% ethanolic extract of Epilobium angustifolium (FEE) (BC-5%FEE and BC-10%FEE, respectively) were prepared. Their mechanical, structural, and antioxidant properties, as well as phenolic acid content, were evaluated. The bioavailability of BC-FESs using mouse L929 fibroblasts as model cells was tested. Moreover, In Vitro penetration through the pigskin of the selected phenolic acids contained in FEE and their accumulation in the skin after topical application of BC-FEEs was examined. The BC-FEEs were characterized by antioxidant activity. The BC-5% FEE showed relatively low toxicity to healthy mouse fibroblasts. Gallic acid (GA), chlorogenic acid (ChA), 3,4-dihydroxybenzoic acid (3,4-DHB), 4-hydroxybenzoic acid (4-HB), 3-hydroxybenzoic acid (3-HB), and caffeic acid (CA) found in FEE were also identified in the membranes. After topical application of the membranes to the pigskin penetration of some phenolic acid and other antioxidants through the skin as well as their accumulation in the skin was observed. The bacterial cellulose membrane loaded by plant extract may be an interesting solution for topical antioxidant delivery to the skin.

show abstract

“…Nanocelluloses with different characteristics are obtained by these processes: (a) microfibrillated, nanofibrillated cellulose or cellulose nanofibrils (CNF), characterized by a higher aspect ratio and flexibility, are obtained by mechanical treatment as the main step and (b) cellulose nanocrystals (CNC) or (nano)whiskers, with lower aspect ratio and high crystallinity, are obtained by acid hydrolysis. CNFs structure contains more amorphous regions than CNCs due to the milder chemical and mechanical treatments applied for the isolation of nanocellulose that do not alter the fibrous structure [ 21 ]. On the contrary, during acid hydrolysis the amorphous regions of cellulose are attacked and disintegrated resulting rod-like rigid high crystalline CNCs [ 22 ].…”

Section: Nanocellulose—isolation From Different Sources Structurementioning

confidence: 99%

Nanocellulose Hybrids with Metal Oxides Nanoparticles for Biomedical Applications

Oprea

Panaitescu

2020

Molecules

Self Cite

View full text Add to dashboard Cite

Cellulose is one of the most affordable, sustainable and renewable resources, and has attracted much attention especially in the form of nanocellulose. Bacterial cellulose, cellulose nanocrystals or nanofibers may serve as a polymer support to enhance the effectiveness of metal nanoparticles. The resultant hybrids are valuable materials for biomedical applications due to the novel optical, electronic, magnetic and antibacterial properties. In the present review, the preparation methods, properties and application of nanocellulose hybrids with different metal oxides nanoparticles such as zinc oxide, titanium dioxide, copper oxide, magnesium oxide or magnetite are thoroughly discussed. Nanocellulose-metal oxides antibacterial formulations are preferred to antibiotics due to the lack of microbial resistance, which is the main cause for the antibiotics failure to cure infections. Metal oxide nanoparticles may be separately synthesized and added to nanocellulose (ex situ processes) or they can be synthesized using nanocellulose as a template (in situ processes). In the latter case, the precursor is trapped inside the nanocellulose network and then reduced to the metal oxide. The influence of the synthesis methods and conditions on the thermal and mechanical properties, along with the bactericidal and cytotoxicity responses of nanocellulose-metal oxides hybrids were mainly analyzed in this review. The current status of research in the field and future perspectives were also signaled.

show abstract

Recent advances in composites based on cellulose derivatives for biomedical applications

Cited by 191 publications

References 139 publications

Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review

Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review

Bacterial Cellulose Membrane Containing Epilobium angustifolium L. Extract as a Promising Material for the Topical Delivery of Antioxidants to the Skin

Nanocellulose Hybrids with Metal Oxides Nanoparticles for Biomedical Applications

Contact Info

Product

Resources

About