Recent Advances in Cell‐Based In Vitro Models to Recreate Human Intestinal Inflammation
Maria Helena Macedo,
Mafalda Dias Neto,
Lorenzo Pastrana
et al.
Abstract:Inflammatory bowel disease causes a major burden to patients and healthcare systems, raising the need to develop effective therapies. Technological advances in cell culture, allied with ethical issues, have propelled in vitro models as essential tools to study disease aetiology, its progression, and possible therapies. Several cell‐based in vitro models of intestinal inflammation have been used, varying in their complexity and methodology to induce inflammation. Immortalized cell lines are extensively used due… Show more
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