Recent Advances in C–H Functionalization of Five–Membered Heterocycles with Single Heteroatoms

Prabagar, B.; Shi, Zhuangzhi

doi:10.1002/9781119774167.ch2

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Transition‐Metal‐Catalyzed C‐H Functionalization of Heterocycles 2023

DOI: 10.1002/9781119774167.ch2

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Recent Advances in C–H Functionalization of Five–Membered Heterocycles with Single Heteroatoms

B. Prabagar¹,

Zhuangzhi Shi²

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2024

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Cited by 2 publications

References 102 publications

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Three-component cascade reaction of 3-ketonitriles, 2-unsubstituted imidazole N-oxides, and aldehydes

Uvarova,

Kutasevich,

Lipatov

et al. 2024

Org. Biomol. Chem.

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Three-component cascade reaction of 3-ketonitriles, 2-unsubstituted imidazole N-oxides, and aldehydes

Uvarova,

Kutasevich,

Lipatov

et al. 2024

Org. Biomol. Chem.

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Simple Access to 3-(Hetero)arylated Derivatives of 2-Furoic Acid via Ru(II)-Catalyzed C3-H Arylation of 2-Furoylimidazole

Chernyshev,

Ananikov,

Shepelenko

et al. 2024

Synthesis

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A new approach for the preparation of a variety of 3-arylated 2-furoic acid derivatives has been developed. The approach involves selective Ru-catalyzed C3-H arylation of the furan moiety of readily available 2-furoyl-1-methylimidazole (using imidazole as a removable N-donor directing group), subsequent N-methylation, and nucleophilic substitution of the imidazole moiety with N, O, S, and C nucleophiles.

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Recent Advances in C–H Functionalization of Five–Membered Heterocycles with Single Heteroatoms

Cited by 2 publications

References 102 publications

Three-component cascade reaction of 3-ketonitriles, 2-unsubstituted imidazole N-oxides, and aldehydes

Three-component cascade reaction of 3-ketonitriles, 2-unsubstituted imidazole N-oxides, and aldehydes

Simple Access to 3-(Hetero)arylated Derivatives of 2-Furoic Acid via Ru(II)-Catalyzed C3-H Arylation of 2-Furoylimidazole

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