Recent advances in black phosphorus-based electrochemical sensors: A review

Li, Qing; Wu, Jing; Liu, Ying; Qi, Xiaoman; Jin, Hong‐Guang; Yang, Chun; Li, Jun; Li, Guangli; He, Quanguo

doi:10.1016/j.aca.2021.338480

Cited by 165 publications

(88 citation statements)

References 162 publications

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“…In addition, BP can be degraded into nontoxic phosphonates and phosphate after the reaction with water and oxygen in vivo, and coincidentally, phosphorus is an important element that exists abundantly in the human body for osteogenesis, which broadens its application as a kind of biodegradable nanomaterial within the body [ 13 ]. From all these mentioned above, BP can be regarded as a safe and multifunctional nanoplatform for anticancer drug delivery [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Black Phosphorus, an Emerging Versatile Nanoplatform for Cancer Immunotherapy

et al. 2021

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Black phosphorus (BP) is one of the emerging versatile nanomaterials with outstanding biocompatibility and biodegradability, exhibiting great potential as a promising inorganic nanomaterial in the biomedical field. BP nanomaterials possess excellent ability for valid bio-conjugation and molecular loading in anticancer therapy. Generally, BP nanomaterials can be classified into BP nanosheets (BPNSs) and BP quantum dots (BPQDs), both of which can be synthesized through various preparation routes. In addition, BP nanomaterials can be applied as photothermal agents (PTA) for the photothermal therapy (PTT) due to their high photothermal conversion efficiency and larger extinction coefficients. The generated local hyperpyrexia leads to thermal elimination of tumor. Besides, BP nanomaterials are capable of producing singlet oxygen, which enable its application as a photosensitizer for photodynamic therapy (PDT). Moreover, BP nanomaterials can be oxidized and degraded to nontoxic phosphonates and phosphate under physiological conditions, improving their safety as a nano drug carrier in cancer therapy. Recently, it has been reported that BP-based PTT is capable of activating immune responses and alleviating the immunosuppressive tumor microenvironment by detection of T lymphocytes and various immunocytokines, indicating that BP-based nanocomposites not only serve as effective PTAs to ablate large solid tumors but also function as an immunomodulation agent to eliminate discrete tumorlets. Therefore, BP-mediated immunotherapy would provide more possibilities for synergistic cancer treatment.

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Section: Introductionmentioning

confidence: 99%

Black Phosphorus, an Emerging Versatile Nanoplatform for Cancer Immunotherapy

et al. 2021

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“…Furthermore, the measurements are easy to set up and above all miniaturization is possible so that electrosensing could be directly Sensors 2021, 21, 4300 2 of 42 done near water sources using portable devices [3]. These features are at the origin of the success story of electrochemical sensors [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Zheng

Khaoulani

Ktari³

et al. 2021

Sensors

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This review critically summarizes the knowledge of imprinted polymer-based electrochemical sensors for the detection of pesticides, metal ions and waterborne pathogenic bacteria, focusing on the last five years. MIP-based electrochemical sensors exhibit low limits of detection (LOD), high selectivity, high sensitivity and low cost. We put the emphasis on the design of imprinted polymers and their composites and coatings by radical polymerization, oxidative polymerization of conjugated monomers or sol-gel chemistry. Whilst most imprinted polymers are used in conjunction with differential pulse or square wave voltammetry for sensing organics and metal ions, electrochemical impedance spectroscopy (EIS) appears as the chief technique for detecting bacteria or their corresponding proteins. Interestingly, bacteria could also be probed via their quorum sensing signaling molecules or flagella proteins. If much has been developed in the past decade with glassy carbon or gold electrodes, it is clear that carbon paste electrodes of imprinted polymers are more and more investigated due to their versatility. Shortlisted case studies were critically reviewed and discussed; clearly, a plethora of tricky strategies of designing selective electrochemical sensors are offered to “Imprinters”. We anticipate that this review will be of interest to experts and newcomers in the field who are paying time and effort combining electrochemical sensors with MIP technology.

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“…Inspired by our few recent reports on electrochemical sensing [20,[26][27][28][29], in this study we have developed an electrochemical impedimetric biosensor using gold-polyaniline nanocomposites (Au-PAni) and nitrogen, sulfur co-doped graphene quantum dots (N,S-GQDs) as the base matrix [30,31]. EIS is very popular in energy storage, battery, and solidstate electrolyte applications [32][33][34], although applications in biosensing devices are also emerging.…”

Section: Introductionmentioning

confidence: 99%

Design and Analysis of a Single System of Impedimetric Biosensors for the Detection of Mosquito-Borne Viruses

et al. 2021

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The treatment for mosquito-borne viral diseases such as dengue virus (DENV), zika virus (ZIKV), and chikungunya virus (CHIKV) has become difficult due to delayed diagnosis processes. In addition, sharing the same transmission media and similar symptoms at the early stage of infection of these diseases has become more critical for early diagnosis. To overcome this, a common platform that can identify the virus with high sensitivity and selectivity, even for the different serotypes, is in high demand. In this study, we have attempted an electrochemical impedimetric method to detect the ZIKV, DENV, and CHIKV using their corresponding antibody-conjugated sensor electrodes. The significance of this method is emphasized on the fabrication of a common matrix of gold–polyaniline and sulfur, nitrogen-doped graphene quantum dot nanocomposites (Au-PAni-N,S-GQDs), which have a strong impedimetric response based only on the conjugated antibody, resulting in minimum cross-reactivity for the detection of various mosquito-borne viruses, separately. As a result, four serotypes of DENV and ZIKV, and CHIKV have been detected successfully with an LOD of femtogram mL–1.

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Recent advances in black phosphorus-based electrochemical sensors: A review

Cited by 165 publications

References 162 publications

Black Phosphorus, an Emerging Versatile Nanoplatform for Cancer Immunotherapy

Black Phosphorus, an Emerging Versatile Nanoplatform for Cancer Immunotherapy

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Design and Analysis of a Single System of Impedimetric Biosensors for the Detection of Mosquito-Borne Viruses

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