Recent advances in biosensor technology in assessment of early diabetes biomarkers

Maghsoudi, Armin Salek; Vakhshiteh, Faezeh; Torabi, Raheleh; Hassani, Shokoufeh; Ganjali, Mohammad Reza; Norouzi, Parviz; Hosseini, Morteza; Abdollahi, Mohammad

doi:10.1016/j.bios.2017.07.047

Cited by 137 publications

(60 citation statements)

References 209 publications

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“…Despite the few advantages like low-priced thin-film applications [4], direct real-time monitoring [7], no reference electrode need and miniaturization possibilities, this technique gives less sensitive responses than others electrochemical methods [2]. Hnaiein et al have implemented this technique for Escherichia coli detection.…”

Section: Electrochemical Sensor: Conductometric Detectionmentioning

confidence: 99%

“…The activity of recognition element varies before and after interaction with a target molecule [4]. The product must be electroactive and undergoes a redox process [12].…”

Section: Electrochemical Sensor: Amperometric Detectionmentioning

confidence: 99%

“…False positive results derived from the electrolytes are the main drawback. It can be overcome by blocking the non-specific binding sites of the electrode surface with, for example, BSA protein [4]. The immunoreaction between antigen and antibody directly indicates impedance changes.…”

Section: Electrochemical Sensor: Impedimetric Detectionmentioning

confidence: 99%

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Application of Electrochemical Methods in Biosensing Technologies

Dziąbowska¹,

Czaczyk²,

Nidzworski³

2018

Biosensing Technologies for the Detection of Pathogens - A Prospective Way for Rapid Analysis

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Introducing biochemical factor to electronic devices have created a new branch of science. Recent development in biosensing technology enabled progress in pathogens detection. Currently, wide range of biomarkers (enzymes, peptides, DNA, microorganisms, etc. ) recognize various target analytes, starting from basic metabolism changes to serious infections caused by pathogens. Improved sensitivity, selectivity and response time of sensors have instantly replaced traditional techniques. Easy handling, low production costs and miniaturization have met therapeutics need. Biosensing technologies are very strong point in telemedicine in public healthcare. This chapter will focus on electrochemical techniques for pathogens detection and show trending applications in biosensing technologies.

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Section: Electrochemical Sensor: Conductometric Detectionmentioning

confidence: 99%

“…The activity of recognition element varies before and after interaction with a target molecule [4]. The product must be electroactive and undergoes a redox process [12].…”

Section: Electrochemical Sensor: Amperometric Detectionmentioning

confidence: 99%

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Application of Electrochemical Methods in Biosensing Technologies

Dziąbowska¹,

Czaczyk²,

Nidzworski³

2018

Biosensing Technologies for the Detection of Pathogens - A Prospective Way for Rapid Analysis

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“…For biosensing, that is, the use of biomolecular probes to measure the concentration of biological molecules, surface plasmon resonance (SPR) sensing devices have been widely studied due to their advantages of high sensitivity, label‐free, real‐time, and rapid detection . SPR sensing is used in various application fields including molecular recognition, biotechnology, medical diagnostics, drug screening, etc .…”

Section: Introductionmentioning

confidence: 99%

“…they are still unable to achieve the direct detection of small biomolecules (of a few hundreds of Daltons). Consequently, various proposals have been developed to enhance the sensitivity or resolution of biosensors . Among them, also different nanostructured surfaces have been considered.…”

Section: Introductionmentioning

confidence: 99%

Stable, nanometer‐thick oxygen‐containing plasma polymer films suited for enhanced biosensing

Hegemann

Индутный

Zajı́čková

et al. 2018

Plasma Processes & Polymers

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Stable surface functionalization is required in many applications such as in biosensing. For this purpose, hydrocarbon‐based plasma polymer films (PPFs) were investigated by controlling cross‐linking and film structure at the nanoscale, while functional groups were incorporated using a CO2/C2H4 low pressure plasma. In particular, an oxygen‐rich termination layer of 1 nm (top layer) was gradually deposited onto a more cross‐linked PPF (base layer) with varying thickness (<20 nm) yielding highly stable yet functional a‐C:H:O films as compared to conventional oxygen‐rich PPFs. Such stabilized nano‐layers provided a homogeneous functionalization of Au‐coated (flat) biochips as used for immunosensing as well as of nanostructured Au‐coated surfaces explored for enhanced biosensing. The used periodic grating coated by the highly stable a‐C:H:O nano‐layer can be adjusted to the required environmental refractive index range yielding a distinct sensitivity enhancement for biosensing.

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