Recent Advances in Biosensor Development for Foodborne Virus Detection

Neethirajan, Suresh; Ahmed, Syed Rahin; Chand, Rohit; Buozis, John; Nagy, Éva

doi:10.7150/ntno.20301

Cited by 41 publications

(34 citation statements)

References 173 publications

(216 reference statements)

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“…Also, food handlers infected with rotavirus may contaminate foods. The infection dose for human is estimated at 10-100 viral particles found in food or water [9]…”

Section: Human Rotavirus (Hrv)mentioning

confidence: 99%

Foodborne Viruses and Innovative Non-Thermal Food-Processing Technologies

Pexara

Govaris

2020

Foods

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In recent years, several foodborne viruses’ outbreaks have been recorded worldwide. Μost of the foodborne viruses have a low infection dose, are stable and can persist and survive in foods for a long time without loss of infectivity. The most important foodborne viruses are: human norovirus (HuNoV), human rotavirus (HRV), hepatitis A virus (HAV), hepatitis E virus (HEV), human astrovirus (HAstV), Aichi virus (AiV), sapovirus (SaV), human adenovirus (HAdV) and enterovirus (EV). In recent years, innovative non-thermal food-processing technologies including high-pressure processing (HPP), cold plasma (CP), ultraviolet light (UV), irradiation and pulsed electric field (PEF) for improving the quality and safety of foods, including foods of animal origin, have been under research. This review presents the recent data on foodborne viruses and reviews the innovative non-thermal technologies for the control of the foodborne viruses in foods.

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“…Also, food handlers infected with rotavirus may contaminate foods. The infection dose for human is estimated at 10-100 viral particles found in food or water [9]…”

Section: Human Rotavirus (Hrv)mentioning

confidence: 99%

Foodborne Viruses and Innovative Non-Thermal Food-Processing Technologies

Pexara

Govaris

2020

Foods

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“…In recent times, menacing diseases caused by viruses, for instance, human immunodeficiency virus (HIV), severe acute respiratory syndrome coronavirus (SARS‐CoV), Nipah, avian influenza, Hendra , etc. have affected human life significantly, thus biosensor can be a beneficial tool for their detection due to their on‐site, real‐time monitoring and early detection capability …”

Section: Introductionmentioning

confidence: 99%

Progress in the Development of Intrinsically Conducting Polymer Composites as Biosensors

Prajapati

Kandasubramanian

2019

Macro Chemistry & Physics

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Biosensors are analytical devices which find extensive applications in fields such as the food industry, defense sector, environmental monitoring, and in clinical diagnosis. Similarly, intrinsically conducting polymers (ICPs) and their composites have lured immense interest in bio‐sensing due to their various attributes like compatibility with biological molecules, efficient electron transfer upon biochemical reactions, loading of bio‐reagent, and immobilization of biomolecules. Further, they are proficient in sensing diverse biological species and compounds like glucose (detection limit ≈0.18 nm), DNA (≈10 pm), cholesterol (≈1 µm), aptamer (≈0.8 pm), and also cancer cells (≈5 pm mL−1) making them a potential candidate for biological sensing functions. ICPs and their composites have been extensively exploited by researchers in the field of biosensors owing to these peculiarities; however, no consolidated literature on the usage of conducting polymer composites for biosensing functions is available. This review extensively elucidates on ICP composites and doped conjugated polymers for biosensing functions of copious biological species. In addition, a brief overview is provided on various forms of biosensors, their sensing mechanisms, and various methods of immobilizing biological species along with the life cycle assessment of biosensors for various biosensing applications, and their cost analysis.

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“…Which, may be explained on basis of their antioxidant activities, scavenging capacities, inhibiting DNA, RNA synthesis, inhibition of the viral entry, or inhibiting the viral reproduction In recent years it has been recognized that viruses are an important cause of food-borne diseases. Enteric viruses are the principal agents for outbreaks of food related illness outbreaks worldwide and are responsible for estimation of about 40-50 million illnesses each year in the United States (Todd andGreig, 2015 andNeethirajan et al 2017). About 40 million (80%) of the illnesses attributed to Noro viruses, Hepatitis A and E virus-Naglaa Saif, Othman, Mohamed and El-Dougdoug es, Adenovirus (types 41 and 42), Rotavirus, Enterovirus that include Coxsackie B viruses, as well as other RNA viruses groups.…”

Section: Introductionmentioning

confidence: 99%

Polyphenolic Wealthy Moringa Leaves Extracts as Anticoxsackie B Viruses (Cox-Bv)

Saif¹,

Othman

Mohamed

et al. 2019

Arab Universities Journal of Agricultural Sciences

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The antiviral role of Moringaoleifera leaves extracts ((chloroform (CL), Ethyl acetate (E.A), methanol 80% (M) and n.butanol (n.b) to control Coxsackie B (COX-BV) viral infection was monitored in vitro compared with human interferon alpha (IFNᾰ-2a) in order to evaluate the antiviral activity of moringa leaves extracts. The phenolic compound was given higher conc. in E.A. extracts. Cytotoxicity was determined for Moringa leaves extracts on viability of HEP2 cell using MTT assay. The 98μg/ml concentrations for four extracts were considerably non-toxic for HEP2 cell line culture. Antiviral activity in Moringa extracts may be attributed to phenolic compounds and / or as a result of stimulation of COX-BV-sensitive HEP2 cells to express MX protein. Antiviral activity of Moringa leaves extracts compared with IFNᾰ-2a to cell lines against COX-BV viral infection was determined by assessment of the COX-BV virus infectivity titer declining rate and relative residual living cell count using End Point Assay, using three ways pretreatment, co-treatment and post-treatment cell line treated with Moringaextracts. It was found that the extract acetyl acetate was better as an MX gene expression level compared with its level in control cells. It was concluded that Moringaleaves extracts have antiviral activity against COX-BV.

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Recent Advances in Biosensor Development for Foodborne Virus Detection

Cited by 41 publications

References 173 publications

Foodborne Viruses and Innovative Non-Thermal Food-Processing Technologies

Foodborne Viruses and Innovative Non-Thermal Food-Processing Technologies

Progress in the Development of Intrinsically Conducting Polymer Composites as Biosensors

Polyphenolic Wealthy Moringa Leaves Extracts as Anticoxsackie B Viruses (Cox-Bv)

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