Recent advances and current challenges of new approach methodologies in developmental and adult neurotoxicity testing
Melania Maria Serafini,
Sara Sepehri,
Miriam Midali
et al.
Abstract:Adult neurotoxicity (ANT) and developmental neurotoxicity (DNT) assessments aim to understand the adverse effects and underlying mechanisms of toxicants on the human nervous system. In recent years, there has been an increasing focus on the so-called new approach methodologies (NAMs). The Organization for Economic Co-operation and Development (OECD), together with European and American regulatory agencies, promote the use of validated alternative test systems, but to date, guidelines for regulatory DNT and ANT… Show more
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