“…Although there is nothing magical about the one-hour mark in trauma, it does represent an important concept; rapid, specialized treatment results in improved clinical outcomes. 1 This time-sensitive concept is applied to a number of high-intensity, critical conditions, including ST-elevation myocardial infarction (STEMI) 2 , cerebrovascular accident (CVA) 3 , out-ofhospital cardiac arrest (OHCA) 4 , and sepsis. 5,6 Since the era of bed rest for the treatment of STEMI in the 1960s 7 , the treatment of this and many other lifethreatening conditions has undergone profound changes, leading to the development of "regionalized systems of care" using hospital-based "centres of excellence," which provide advanced diagnostics, interventions, and expertise not routinely available in typical referral hospitals.…”