Receipt of pertussis vaccine during pregnancy across 7 Vaccine Safety Datalink Sites

Pertussis vaccination in pregnancy

“…54 A small but statistically significant increased risk of a recorded diagnosis of chorioamnionitis was found in a retrospective cohort study of pregnant women from 2 VSD sites between 2010 to 2012, although the magnitude of this risk was lower in those immunized during the third trimester. 56 However, it was not possible to adjust for other chorioamnionitis risk factors in the cohort and there was no increased risk of preterm birth, a major sequela of chorioamnionitis. This finding should therefore be interpreted with caution due to residual confounders and the fact that only there was only a 50% positive predictive value for having a clinical presentation consistent with chorioamnionitis in those given the diagnosis, reflecting the difficulty in reliably diagnosing chorioamnionitis.…”

Effect of Mobile Phone Text Message Reminders on Routine Immunization Uptake in Pakistan: Randomized Controlled Trial (Preprint)

“…Qualitative studies conducted in the US have also shown parents acceptability for text message immunization reminders, factors affecting mothers/caregivers' decision to vaccinate their child and benefits of receiving text for immunizations [34,35]. Further SMS text messages content were explored with parents/caregivers in order to prompt them to schedule their child's immunization appointment [36].…”

Suffer the Infants: A Severe Case of Pertussis in Oregon, 2012

“…Several recently published studies show low Tdap coverage among pregnant women. 10,11 Obstetricians and public health officials need to explore ways to boost vaccination rates among pregnant women during every pregnancy. …”