In recent years, much attention has been paid to treat cardiovascular diseases by laser techniques. That is, 1) Transmyocardial laser revascularization (TMLR) for end-stage of ischemic heart disease, 2) Laser vascular anastomosis, 3) Laser vascular angioplasty, these three categories are documented as follows. We have each performed experimentally and done clinically well, because of good experimental results. Consequently, feasibility of endovascular laser intervention could be recognized for the treatment of peripheral arterial diseases.