Recalcitrant subungual verruca of a child successfully treated with combination use of traditional Japanese herbal medicines, shokenchuto and makyoyokukanto

Kobayashi, Hiromi; Tsuruta, Daisuke; Tamiya, Hisashi; Yanagihara, Shigeto; Nakanishi, Takeshi; Mizuno, Nobuyuki; Ishii, Masamitsu

doi:10.1111/j.1346-8138.2011.01203.x

Cited by 3 publications

(2 citation statements)

References 7 publications

(10 reference statements)

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“…It contains a lot of fatty oils and fatty acids, and their esters have become the main chemical components in it. Combination of Ephedra herb and coix seed is applied to treat impediment pain, muscle cramp and pain, hydrops, and verruca [22].…”

Section: Discussionmentioning

confidence: 99%

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Makyoyokukanto use in patients with painful afflictions

Hirasawa,

Nakae,

Tanaka

et al. 2023

Pers Med Univers

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Aim: Makyoyokukanto (MKYK) is a traditional Japanese medicine used for relieving arthralgia, neuralgia, and myalgia. However, the effectiveness and safety of MKYK remains unclear. In this study, we assessed the effectiveness of MKYK in patients with painful afflictions.Methods: One hundred and sixty-three patients (42 men and 121 women) with painful afflictions were recruited into the study. All participants were treated using non-invasive methods and administered MKYK. The effectiveness of MKYK was assessed following administration by evaluating the need for NSAIDs or other medication. In addition, adverse reactions were monitored.Results: 85.9% of the patients were effectively treated with MKYK. Comorbidities were present in 52.8% of the study participants. The median duration of MKYK treatment was 14 days (2 364 days). The adverse event rate was 1.2%. The adverse events were insomnia caused by Ephedra herb and pseudoaldosteronism by Glycyrrhiza root. All symptoms improved after MKYK withdrawal. Conclusion:The adverse event rate associated with MKYK use was low, and its onset was relatively rapid. This adverse event rate can be further reduced by focusing on the pharmacological action of Ephedra herb and Glycyrrhiza root. This study suggests that MKYK can be used more widely for painful afflictions.

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Section: Discussionmentioning

confidence: 99%

“…MKYK is composed of Ephedra herb, apricot kernel, coix seed, and Glycyrrhiza root. MKYK has also been used to treat arthrosis deformans, rheumatoid arthritis, eczema, cold, influenza, and verruca [3,4]. However, the incidence of adverse events associated with MKYK remains unclear [5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%