“…A sample of at least 870 participants (in a between-subject design), or 435 subjects (in a within-subject design), which is over 26 to 54 (within-subject 13 to 26) times greater than previous investigations, would 6 These include RMET baseline scores, portion A or B, 2D:4D and treatment interactions, Cognitive Reflection Task (CRT) scores, math abilities, mood and affective measures, treatment expectancy, age, marital status, sexual preference, and all other measured hormones that were not influenced by T treatment. The CRT control was added because performance is impaired by exogenous T (Gideon Nave, Nadler, Zava, & Camerer, 2017) and people with ASD outperform non-ASD age-matched controls (Brosnan, Lewton, & Ashwin, 2016). 7 These include Cognitive Reflection Task (CRT) scores, factor 1 and 2 psychopathy measures, treatment expectancy, age, marital status, sexual preference, and all other measured hormones that were not influenced by T treatment.…”