Rearranged iridal-type triterpenoids from Iris tectorum

Bioactive Usual and Unusual Triterpenoids Derived from Natural Sources Used in Traditional Medicine

“…The compounds 136 -138 displayed weak antibacterial activity against Micrococcus lysodeikticus, Bacterium paratyphosum B, and Pseudomonas aeruginosa with a MIC value of 100 μM. [124]…”

“…The marginal antiparasitic activity of compounds 134 and 135 showed against Trypanosoma cruzi and Leishmania mexican a strains [123] . Adiantum (Adiantaceae), also referred to as maidenhair ferns, are used for dietary purposes, as medicine for treating respiratory ailments, and as an astringent, emmenagogue, diuretic, and demulcent [124] . From a 95 % ethanol extract of the aerial portions of A. capillus‐veneris , three hopanes were isolated fern‐7(8)‐en‐19 α , 28‐diol ( 136 ), pteron‐14‐ene‐7 α ,19 α ,28‐triol ( 137 ), and 3 β ,4 α ,25‐trihydroxyfilican ( 138 ).…”

“…The compounds 137 and 138 were tested for their antifungal activity against agricultural pathogenic fungi, including Sclerotinia sclerotiorun , Helminthosporium maydis , Verticillium dahliae Kleb , Phytophthora parasitica , Gibberella saubinetii , Alternaria alternata , Botrytis cinerea Pers ., and Colletotrichum acutatum Simmonds , which showed remarkable antifungal activity against H. maydis and A. alternata with minimum inhibitory concentration (MIC) values of 12.5–3.125 μM, and compound 138 showed remarkable activity against V. dahliae Kleb with a MIC value of 3.125 μM. The compounds 136 – 138 displayed weak antibacterial activity against Micrococcus lysodeikticus , Bacterium paratyphosum B , and Pseudomonas aeruginosa with a MIC value of 100 μM [124] …”

“…[106] Endodesmia calophylloides Benth., the single tree species of the genus Endodesmia, family Guttiferae, an African monotypic genus found in Angola, Gabon, Cameroon, and Nigeria, is not employed in any traditional medical system. Endodesmiadiol (121), friedelin (122), canophyllol (123), and canophyllal (124) were isolated, and an ethyl acetate extract of the stem bark of E. calophylloides (resistant to chloroquine and other antimalarial drugs) was tested for effectiveness against the W2 strain of Plasmodium falciparum. Antiplasmodial action was observed for compounds 121 -124, with IC 50 values of 13.0, 7.2, 15.0, and 18.2 mM, respectively.…”

“…[123] Adiantum (Adiantaceae), also referred to as maidenhair ferns, are used for dietary purposes, as medicine for treating respiratory ailments, and as an astringent, emmenagogue, diuretic, and demulcent. [124] From a 95 % ethanol extract of the aerial portions of A. capillus-veneris, three hopanes were isolated fern-7(8)-en-19α, 28-diol (136), pteron-14-ene-7α,19α,28-triol (137), and 3β,4α,25-trihydroxyfilican (138). The compounds 137 and 138 were tested for their antifungal activity against agricultural pathogenic fungi, including Sclerotinia sclerotiorun, Helminthosporium maydis, Verticillium dahliae Kleb, Phytoph-thora parasitica, Gibberella saubinetii, Alternaria alternata, Botrytis cinerea Pers., and Colletotrichum acutatum Simmonds, which showed remarkable antifungal activity against H. maydis and A. alternata with minimum inhibitory concentration (MIC) values of 12.5 -3.125 μM, and compound 138 showed remarkable activity against V. dahliae Kleb with a MIC value of 3.125 μM.…”