Reaming Irrigator Aspirator system: Early experience of its multipurpose use

Kanakaris, Nikolaos K.; Morell, D.; Gudipati, S.; Britten, S.; Giannoudis, Peter V.

doi:10.1016/s0020-1383(11)70009-2

Cited by 55 publications

(36 citation statements)

References 49 publications

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“…Since its introduction, the indications for use of RIA have been further extended to include the treatment of postoperative osteomyelitis (69) and the harvesting of mesenchymal stem cells (MSCs) (70). The innovation driven by the RIA systems was so significant, that the Journal "Injury" has dedicated a complete issue to the data available on RIA and its applications recently (71). A systematic review on the Reamer-irrigator-aspirator indications and clinical results has recently been published by Cox et al (72).…”

Section: Bone Grafting and Bone Substitutes In The Last 4 000 Yearsmentioning

confidence: 99%

Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective

et al. 2013

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The role of Bone Tissue Engineering in the field of Regenerative Medicine has been the topic of substantial research over the past two decades. Technological advances have improved orthopaedic implants and surgical techniques for bone reconstruction. However, improvements in surgical techniques to reconstruct bone have been limited by the paucity of autologous materials available and donor site morbidity. Recent advances in the development of biomaterials have provided attractive alternatives to bone grafting expanding the surgical options for restoring the form and function of injured bone. Specifically, novel bioactive (second generation) biomaterials have been developed that are characterised by controlled action and reaction to the host tissue environment, whilst exhibiting controlled chemical breakdown and resorption with an ultimate replacement by regenerating tissue. Future generations of biomaterials (third generation) are designed to be not only osteoconductive but also osteoinductive, i.e. to stimulate regeneration of host tissues by combining tissue engineering and in situ tissue regeneration methods with a focus on novel applications. These techniques will lead to novel possibilities for tissue regeneration and repair. At present, tissue engineered constructs that may find future use as bone grafts for complex skeletal defects, whether from post-traumatic, degenerative, neoplastic or congenital/developmental "origin" require osseous reconstruction to ensure structural and functional integrity. Engineering functional bone using combinations of cells, scaffolds and bioactive factors is a promising strategy and a particular feature for future development in the area of hybrid materials which are able to exhibit suitable biomimetic and mechanical properties. This review will discuss the state of the art in this field and what we can expect from future generations of bone regeneration concepts.

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Section: Bone Grafting and Bone Substitutes In The Last 4 000 Yearsmentioning

confidence: 99%

Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective

et al. 2013

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“…However, concerns about donor-site morbidity, complications and availability are well known [1][2][3]. For this reason many alternatives have been studied over the last decades, but no single alternative contains all the properties of autologous bone.…”

Section: Introductionmentioning

confidence: 99%

Increased osteogenic capacity of Reamer/Irrigator/Aspirator derived mesenchymal stem cells

Bel

Blokhuis

2014

Injury

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“…Vascularised bone transfer has also limited application, associated with high donor site morbidity and requires specialist equipment and expertise. Little instructive experience with such cases has been previously reported, we present our strategy combining developing technologies such as the induced membrane defect reconstruction (or else ''Masquelet'' technique [10]), the use of local antifungal and antibacterial cement spacer [11,12], the RIA system [13], and the application of composite graft [14] according to the ''Diamond'' concept [1,2] (morsellised autograft and potent osteoinductive agent in the form of BMP-7) with established fixation techniques such as the classic angle stable plating system (958 condylar blade plate).…”

Section: Discussionmentioning

confidence: 99%

Management of infected non-union of the proximal femur: A combination of therapeutic techniques

Goff

Kanakaris²

2014

Injury

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Reaming Irrigator Aspirator system: Early experience of its multipurpose use

Cited by 55 publications

References 49 publications

Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective

Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective

Increased osteogenic capacity of Reamer/Irrigator/Aspirator derived mesenchymal stem cells

Management of infected non-union of the proximal femur: A combination of therapeutic techniques

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