Realization of a Prototype Industrial on-Line Sensing System for Ammonium Based on Micro System Technology: Results and Future Perspectives

Krog, Jens Peter; Dirac, H.; Fabius, Birgit; Gravesen, Peter; Daridon, Antoine; Lichtenberg, Jan; Verpoorte, Elisabeth; Rooij, N. F. de; Pennarun-Thomas, GaëIle; Sequeira, Margaret; Diamond, Dermot; Denninger, Mark; Geschke, Oliver; Kutter, Jörg Peter; Howitz, S.; Strec, Cyril; Charles, Philippe; Cognet, Louis

doi:10.1007/978-94-017-2264-3_98

Cited by 2 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Concentrations are expressed in terms of ppm N present in the form of NH 4 + . Absorbance was measured in the optical cuvette drilled in the Pyrex wafer (525 µm thick) by SAE [8,11] (total path-length including depths of inlet and outlet channels (30 µm each): 585 µm), and compared with the absorbance measured in a silicon optical cuvette formed by deep reactive-ion-etching (optical pathlength: 400 µm) [7] Fig. 6 Initial part of the absorbance profile of indophenol blue solution plugs for two different geometries.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Multi-layer microfluidic glass chips for microanalytical applications

Daridon

Fascio

Lichtenberg

et al. 2001

Fresenius J Anal Chem

Self Cite

View full text Add to dashboard Cite

A new, versatile architecture is presented for microfluidic devices made entirely from glass, for use with reagents which would prove highly corrosive for silicon. Chips consist of three layers of glass wafers bonded together by fusion bonding. On the inside wafer faces a network of microfluidic channels is created by photolithography and wet chemical etching. Low dead-volume fluidic connections between the layers are fabricated by spark-assisted etching (SAE), a computer numerical controlled (CNC)-like machining technique new to microfluidic system fabrication. This method is also used to form a vertical, long path-length, optical cuvette through the middle wafer for optical absorbance detection of low-concentration compounds. Advantages of this technique compared with other, more standard, methods are discussed.When the new glass-based device for flow-injection analysis of ammonia was compared with our first-generation chips based on silicon micromachining, concentration sensitivity was higher, because of the longer pathlength of the optical cuvette. The dependence of dispersion on velocity profile and on channel cross-sectional geometry is discussed. The rapid implementation of the devices for an organic synthesis reaction, the Wittig reaction, is also briefly described.

show abstract

Section: Resultsmentioning

confidence: 99%

“…The first generation of devices, consisting of a silicon chip with dry-etched channels sandwiched between two Pyrex chips, proved the feasibility of the microfluidic approach [8]. At the flow rates used in these devices (µL min -1 ), flow velocity profiles have the parabolic shape typical of pressure-driven laminar flow.…”

Section: Introductionmentioning

confidence: 99%