Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial

Abstract

Reality orientation enhances the effects of donepezil on cognition in Alzheimer's disease.

Alzheimer's disease and implicit memory

“…Its objective is creating environmental stimuli that have eased the temporal and spatial orientation of the patient 83 . other technique employed in this same approach is the reminiscent therapy (RT).…”

Support at Home: Interventions to Enhance Life in Dementia (SHIELD) – evidence, development and evaluation of complex interventions

“…The other studies did not provide information regarding where groups were held. 49,51,53 All of the studies reported on attrition to the programme, although the intention-to-treat analysis plan was described in only two. 6,51 Given the nature of the condition and the age of the participants, attrition in several studies was remarkably small, with zero attrition recorded in six studies [48][49][50]52,59,60 out of 180 participants.…”

“…47 Two reviewers independently assessed eligibility. Of the 94 references, nine studies met the inclusion criteria [48][49][50][51][52][53][54][55] and were included in the analysis. Three recent studies were left awaiting classification.…”

“…Onder et al 53 described how family caregivers were trained by a multidisciplinary team and given a manual and specific schedule for each session. No records were made, however, of how often caregivers delivered the sessions or how closely the manual was followed.…”

“…Data were identified, included and pooled from the 15 included RCTs, 6,[48][49][50][51][52][53][54][55][59][60][61][62][63][64] with a total of 718 participants (407 in experimental groups and 311 in control groups). Analyses were adjusted to the random-effects model, owing to the heterogeneity of trials, and SMDs, because trials used different measures to assess the same outcomes.…”