Real-world Study on the Effect of PARPi as Maintenance Therapy on
Platinum Sensitivity after First- and Second-line Chemotherapy in
Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer
Yanglong Guo,
Xi Chen,
Xuedong Tang
et al.
Abstract:Background:
This study investigated the effect of poly(ADP-ribose) polymerase inhibitors
(PARPi) as maintenance therapy after first- and second-line chemotherapy on platinum sensitivity
in patients with recurrent high-grade serous epithelial ovarian cancer (rHGSOC).
Methods:
This study retrospectively analyzed 172 patients with rHGSOC treated at Zhejiang Cancer
Hospital and Jiaxing Maternity and Child Health Care Hospital between January 2017 and December
2021. The 1st-PARPi group comprised patients who rece… Show more
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