Real-World Evidence in Prescription Medication Use Among U.S. Adults with Neck Pain

Huang, Jinfeng; Meng, Zhou; Zheng, Xuan-Qi; Qin, Zongshi; Sun, Xiaolei; Zhang, Kai; Tian, Haijun; Wang, Xiaobing; Gao, Ze; Li, Yan Michael; Wu, Ai-Min

doi:10.1007/s40122-020-00193-1

Cited by 6 publications

(5 citation statements)

References 58 publications

(67 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consequently, researchers have begun to explore various interventions to prevent the onset of neck pain and halt its progression to chronic pain and disability [32]. The use of medication and other interventions to prevent the occurrence of neck pain in asymptomatic high-risk individuals has been found to incur greater costs than benefits, thus these methods are not indicated [35,36]. A meta-analysis revealed that health education does not prevent the P r e p r i n t onset of neck and back pain [37].…”

Section: Discussionmentioning

confidence: 99%

Temporal Trends in Neck Pain Prevalence among Adolescents and Young Adults Aged 10-24 from 1990 to 2019

Fu,

Liu,

et al. 2024

Arch Med Sci

View full text Add to dashboard Cite

IntroductionNeck pain is common among adolescents and young adults, affecting their health and well-being. However, research on its prevalence trends in this demographic is limited despite its global significance.Material and methodsData from the Global Burden of Disease Study was used to analyze neck pain prevalence and trends among individuals aged 10 to 24 from 1990 to 2019. Temporal trends and regional differences were assessed using estimated annual percentage changes.ResultsGlobally, the number of adolescents and young adults affected by neck pain increased from 11,594,119 cases in 1990 to 12,880,134 in 2019. Despite this increase, the prevalence rate stabilized, dropping from 74,850.57 per 100,000 individuals in 1990 to 69,178.4 per 100,000 in 2019, with an annual decrease of -0.28%. In 2019, prevalence rates for ages 10-14, 15-19, and 20-24 were 31,624.66, 69,189.45, and 109,351.52 per 100,000 individuals, respectively. The regions with the highest prevalence rates in 2019 were Western Europe, High-income North America, and Southeast Asia, with rates of 1938.57, 1930.2, and 1021.37 per 100,000 individuals, respectively. Nationally, the United Kingdom, Denmark, and Finland had the highest rates, reaching 2,487.30, 2,442.03, and 2,336.94 cases per 100,000 individuals, respectively. Notably, regions with higher Socio-Demographic Index (SDI) levels tended to have higher prevalence rates of neck pain among adolescents and young adults, with variations by region and age group.ConclusionsThe study emphasizes the ongoing burden of neck pain among adolescents and young adults worldwide, emphasizing the necessity for targeted interventions to enhance public health outcomes in this group.

show abstract

Section: Discussionmentioning

confidence: 99%

Temporal Trends in Neck Pain Prevalence among Adolescents and Young Adults Aged 10-24 from 1990 to 2019

Fu,

Liu,

et al. 2024

Arch Med Sci

View full text Add to dashboard Cite

show abstract

“…38 However, this outcome was partly contrary to previous studies pointed that lower education level was a risk factor for opioids use. 39,40 A possible explanation for this might be that previous studies were focus on low back pain and neck pain patients with lower average age. So, education level may play a nonsignificant role in older populations.…”

Section: Discussionmentioning

confidence: 99%

Prescription analgesic medication use among osteoarthritis patients

Huang,

Chen,

Gan

et al. 2023

J Orthop Surg (Hong Kong)

View full text Add to dashboard Cite

Objective Pharmacotherapy is the most common strategies to reduce pain for osteoarthritis (OA) patients. To analyze the trend and pattern of prescription analgesic medication use in American OA patients. Besides, our study also tried to figure out the demographic characteristics of opioid use among OA population which may helpful for managing the use of opioids. Methods We included 2214 OA patients from 2007 to 2018. We extracted data from National Health and Nutrition Examination Survey (NHANES) database. We compared analgesics and anti-depression medications use by category between survey participants with OA and without. Results For OA patients, NSAIDs, acetaminophen and gabapentinoid were the mostly highly used analgesics (10.2%, 9.0% and 8.9%, respectively). However, we also found that opioids use was very common in OA patients (7.7%) and the duration of opioids use was significantly long. In addition, the opioids use did not decrease from 2007 to 2018, while gabapentinoid increased rapidly from recent decade (From 5.0% to 12.1%). The common analgesic combination used by OA population was opioids with acetaminophen and gabapentinoid with selective serotonin reuptake inhibitors (SSRIs) (2.9% and 2.7%, respectively). Conclusion The use of gabapentinoid increased rapidly from recent decade, while opioids use did not decrease. The long-term excessive use of opioids was also a serious problem for OA pain control. More improvements such as focusing more on healthcare education and paying more attention on non-pharmacotherapy and the psychological situation of patients are needed.

show abstract

“…In 2020, prescription opioids remained the most commonly misused prescription drug in the United States. Despite guideline recommendations and the widespread use of opioid analgesics, there is no rigorous evidence to support their use for acute LBP and neck pain 8 .…”

Section: Bodymentioning

confidence: 99%

OPAL trial: challenging the use of opioid analgesics for acute low back pain and neck pain: a milestone in evidence-based medicine

Akhtar,

Fareed,

Siblini

2023

Annals of Medicine &Amp; Surgery

View full text Add to dashboard Cite

Real-World Evidence in Prescription Medication Use Among U.S. Adults with Neck Pain

Cited by 6 publications

References 58 publications

Temporal Trends in Neck Pain Prevalence among Adolescents and Young Adults Aged 10-24 from 1990 to 2019

Temporal Trends in Neck Pain Prevalence among Adolescents and Young Adults Aged 10-24 from 1990 to 2019

Prescription analgesic medication use among osteoarthritis patients

OPAL trial: challenging the use of opioid analgesics for acute low back pain and neck pain: a milestone in evidence-based medicine

Contact Info

Product

Resources

About