Real-world Early Outcomes and Retreatment Rates Following Water Vapour Ablative Therapy for Symptomatic Benign Prostatic Hyperplasia

Whiting, Danielle; Noureldin, Mohamed; Abdelmotagly, Yehia; Johnston, Maximilian J.; Brittain, J.E.; Rajkumar, Govindaraj; Emara, Amr; Hindley, Richard G.

doi:10.1016/j.euros.2022.03.006

Cited by 16 publications

(10 citation statements)

References 12 publications

(18 reference statements)

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“…Currently, one of the questions asked regarding the Rezum procedure is the continuity of symptomatic improvement and the need for reoperation. In Whiting et al 's study, 4.6% of the patients required retreatment (10). The most common causes of reoperation were the presence of the median lobe, bladder neck stenosis, and asymmetric prostate cavity in a few patients.…”

Section: Discussionmentioning

confidence: 95%

“…While the increase in Qmax three months after the intervention was 62%, this rate increased to 85% in the 12th month. On the other hand, PVR decreased by 45% on average in the third postoperative month and was found to be similar in the 12th month (10). In their prospective, randomized controlled trial involving 188 patients with a prostate volume of 30-80 g, McVary et al shared their outcomes (11).…”

Section: Discussionmentioning

confidence: 99%

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The Rezum procedure in benign prostate hyperplasia: Initial experience at a single center in Turkey

Kılıç

Balbay

2023

Endourol Bull

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Objective: In this study, we aimed to present our initial experiences with the Rezum procedure, including voiding and sexual outcomes.Material and Methods: A total of 24 patients who underwent the Rezum procedure between June 2021 and August 2022 were included in this retrospective study. For each procedure, 2 to 12 injections were applied to the median and lateral prostate lobes. We analyzed the baseline and follow-up data and compared the outcomes of patients with and without the median lobe of the prostate.Results: The mean follow-up time was 7.5 months. The International Prostate Symptom Score decreased in all patients by 15 points on average (p<0.001), while the maximum urinary flow increased by 5 mL/s on average in all patients except three who had similar values (p<0.001). The post-void residual decrease was 55 mL (p<0.001). In terms of the variables examined, there was no significant difference between patients who had a median lobe and those who had not. Neither any sexual worsening nor any major complications were observed. As for minor complications, two patients had macrohematuria, four had dysuria that required non-steroidal anti-inflammatory drug therapy, and two required re-catheterization due to urinary retention.Conclusion: The Rezum procedure is an effective and practical method, even in patients who have median lobes of the prostate, and preserves sexual functions.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

The Rezum procedure in benign prostate hyperplasia: Initial experience at a single center in Turkey

Kılıç

Balbay

2023

Endourol Bull

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“…A retrospective study ( n = 211) that included 42 patients with a prostate ≥80 ml revealed that prostate volume ≥80 ml was associated with a higher risk of reoperation (odds ratio 4.29, 95% CI 1.15–15.1; p = 0.024), with 9.5% of the large-gland cohort undergoing retreatment (4/42) [22] . However, a multisite prospective observational study of 461 patients ( n = 83 with prostate ≥80 ml) by Whiting et al [23] found no significant difference in the retreatment rate at 1 yr between groups with small and large glands (2.7% vs 3.6%; p = 0.07).…”

Section: Discussionmentioning

confidence: 96%

Prospective Trial of Water Vapor Thermal Therapy for Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia in Subjects with a Large Prostate: 6- and 12-month Outcomes

Woo,

Levin,

Cantrill

et al. 2023

European Urology Open Science

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“… 63 Only one real-world experience with WVTT could be considered of good quality, and even though the follow-up is short (16.7 months), the authors report a re-treatment rate of 4.6%. 64 …”

Section: Evidence Synthesis and Guideline Recommendationsmentioning

confidence: 99%

Minimally invasive surgical therapies (MISTs) for lower urinary tract symptoms (LUTS): promise or panacea?

Busetto,

Checchia,

Recchia

et al. 2023

Asian Journal of Andrology

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The increasing importance of treatment of lower urinary tract symptoms (LUTS), while avoiding side effects and maintaining sexual function, has allowed for the development of minimally invasive surgical therapies (MISTs). Recently, the European Association of Urology guidelines reported a paradigm shift from the management of benign prostatic hyperplasia (BPH) to the management of nonneurogenic male LUTS. The aim of the present review was to evaluate the efficacy and safety of the most commonly used MISTs: ablative techniques such as aquablation, prostatic artery embolization, water vapor energy, and transperineal prostate laser ablation, and nonablative techniques such as prostatic urethral lift and temporarily implanted nitinol device (iTIND). MISTs are becoming a new promise, even if clinical trials with longer follow-up are still lacking. Most of them are still under investigation and, to date, only a few options have been given as a recommendation for use. They cannot be considered as standard of care and are not suitable for all patients. Advantages and disadvantages should be underlined, without forgetting our objective: treatment of LUTS and re-treatment avoidance.

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Real-world Early Outcomes and Retreatment Rates Following Water Vapour Ablative Therapy for Symptomatic Benign Prostatic Hyperplasia

Cited by 16 publications

References 12 publications

The Rezum procedure in benign prostate hyperplasia: Initial experience at a single center in Turkey

The Rezum procedure in benign prostate hyperplasia: Initial experience at a single center in Turkey

Prospective Trial of Water Vapor Thermal Therapy for Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia in Subjects with a Large Prostate: 6- and 12-month Outcomes

Minimally invasive surgical therapies (MISTs) for lower urinary tract symptoms (LUTS): promise or panacea?

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