Real world data on clinical profile, management and outcomes of venous thromboembolism from a tertiary care centre in India

Singh, Suvir; Kapoor, Samir; Singh, Bhupinder; Tandon, Rohit; Singla, Sonaal; Singla, Tanvi; Bansal, Vasu; Singh, Gagandeep; Goyal, Abhishek; Chhabra, Shibba Takkar; Aslam, Naved; Wander, Gurpreet Singh; Mohan, Bishav

doi:10.1016/j.ihj.2021.02.006

Cited by 7 publications

(6 citation statements)

References 30 publications

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“…After removing duplicates and irrelevant articles, 412 full-text articles were assessed for eligibility. Fifty articles were considered eligible for the final synthesis of evidence in a systematic review and meta-analysis, 3 , 4 , 5 , 6 , 7 , 8 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 representing a total of 435,768 patients with PE, of whom 288,258 presented with isolated PE. Systematic DNA analysis was performed in 13 studies.…”

Section: Resultsmentioning

confidence: 99%

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis

Cate¹,

Prochaska²,

Schulz³

et al. 2023

eClinicalMedicine

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Section: Resultsmentioning

confidence: 99%

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis

Cate¹,

Prochaska²,

Schulz³

et al. 2023

eClinicalMedicine

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“…In Kamerkar et al (2016) study, among the total 549 diagnosed venous thromboembolism cases, 0.9% had a history of long-distance travel, including air travel. Singh S et al (Singh et al, 2021) study had identified a history of recent travel of 2 patients among the total 73 VTE patients who had some exiting risk factors.…”

Section: Discussionmentioning

confidence: 99%

Risk of Venous Thromboembolism Among Individuals who Frequently Travel by Flight for Work

Sarkar,

Srivastava,

Mani

et al. 2023

IJALSR

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Many research studies have found that venous thromboembolism is common among frequent travellers in all form mainly air travel. Few Indian studies in acute care settings had also mentioned travel history as an important element. Nowadays a section of corporate employees are frequent flyers in India. Hence, we conducted a pilot project to assess and analyze the risk category among these employees. A snowball sampling was used as a sampling technique. The data collection method was done using a google survey link. An anonymous questionnaire link with a unique code of four digit inserted by the participants, had been circulated among the identified study participants. Out of the total 30 respondents, 13 (43.3%) were at high risk, 8(26.7%) at medium risk and 9 (30%) at low-risk categories of venous thromboembolism development. Pre-existing risk factors and post-travel observation (within 8 weeks of flight travel) were recorded and analysed with SPSS 22 version. Family history was significantly associated with risk category of the employees with chi-square (χ²) value of 22.46 (p<0.05). For high-risk category employees, the venous thromboembolism risk was increased by 44 times (OR 44, 95% CI 3.4-573.4) and for medium-risk category employees 13 times (OR 13.3, 95% CI 1.07-166.4) with the history of infectious disease exposure. Overall presence of certain pre-existing clinical parameters (like heart disease, congenital heart disease, varicose veins, pregnancy, exposure to infectious disease) were significantly associated with a chi-square (χ²) value of 6.09 (p<0.05). Further knowledge level and practice level of these frequent corporate flyers had a statistically significant association with their risk category. This paved the way to develop holistic need-based guidelines covering all relevant key aspects of venous thromboembolism including the head-neck-foot exercise to prevent venous thromboembolism while flying.

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“…Venous thromboembolism (VTE) is a common cardiovascular disease that can manifest as deep vein thrombosis (DVT), pulmonary embolism (PE), or both [1,2]. It usually results in significant non-specific symptoms and health issues such as leg pain and swelling, shortness of breath, and chest pain [1,3,4]. VTE is one of the leading causes of mortality and disability worldwide [5].…”

Section: Introductionmentioning

confidence: 99%

“…It is considered as a public health concern due to its devastating long-term outcomes which include recurrence, post-thrombotic syndrome (PTS), major bleeding due to anticoagulant therapy, chronic thromboembolic pulmonary hypertension, and death. These outcomes place a significant burden on VTE patients and their families [1,3].…”

Section: Introductionmentioning

confidence: 99%

The Length of Hospital Stay of Patients with Venous Thromboembolism: A Cross-Sectional Study from Jordan

et al. 2023

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Background and Objectives: Venous thromboembolism is one of the leading causes of mortality and disability worldwide. Treatment with anticoagulation therapy is essential and requires a delicate approach to select the most appropriate option to improve patient outcomes, including the length of hospital stay (LOS). The aim of this study was to determine the LOS among patients with acute onset of VTE in several public hospitals in Jordan. Materials and Methods: In this study, we recruited hospitalized patients with a confirmed diagnosis of VTE. We reviewed the electronic medical records and charts of VTE admitted patients in addition to a detailed survey to collect the patients’ self-reported data. Hospital LOS was categorized into three levels: 1–3 days, 4–6 days, and ≥7 days. An ordered logistic regression model was used to study the significant predictors of LOS. Results: A total of 317 VTE patients were recruited, with 52.4% of them were male and 35.3% aged between 50 and 69 years. Most patients had a deep vein thrombosis (DVT) diagnosis (84.2%), and most of the VTE cases were admitted for the first-time (64.6%). The majority of the patients were smokers (57.2%), overweight/obese (66.3%), and hypertensive (59%). Most of the VTE patients received Warfarin overlapped with low molecular weight heparins as their treatment regimen (>70%). Almost half of the admitted VTE patients (45%) were hospitalized for at least 7 days. Longer LOS was significantly associated with hypertension. Conclusions: We recommend using therapies that have been proven to reduce hospital LOS, such as non-vitamin K antagonist oral anticoagulants or direct oral anticoagulants, to treat VTE patients in Jordan. Additionally, preventing and controlling comorbidities such as hypertension is essential.

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Real world data on clinical profile, management and outcomes of venous thromboembolism from a tertiary care centre in India

Cited by 7 publications

References 30 publications

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis

Risk of Venous Thromboembolism Among Individuals who Frequently Travel by Flight for Work

The Length of Hospital Stay of Patients with Venous Thromboembolism: A Cross-Sectional Study from Jordan

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