Real-World Data Analysis of CDK4/6 Inhibitor Therapy—A Patient-Centric Single Center Study
Isabell Ge,
Kai Berner,
Marlene Mathis
et al.
Abstract:Background: The quest to comprehend the real-world efficacy of CDK4/6 inhibitors (CDKis) in breast cancer continues, as patient responses vary significantly. Methods: This single-center retrospective study evaluated CDKi use outside the trial condition from November 2016 to May 2020. Progression-free survival (PFS), time-to-treatment failure (TTF), short-term and prolonged treatment benefit (≥4 and ≥10 months), as well as prognostic and predictive markers were assessed with Kaplan–Meier and multivariate regres… Show more
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