“…As a result the hemispheric PISA method has been [14] found significant underestimation of the EROA determined using the conventional hemispheric PISA method compared to the EROA measured by hemielliptic PISA, particularly in patients with MVP and functional MR. Hemielliptic PISA can be obtained from RT3DE datasets using PISA width, length, and radius for the calculation of the hemielliptic PISA surface by a hemielliptic formula (. 7 [102] or investigated computer simulations for semi-automated 3D reconstruction of PISA [103] and found significantly improved accuracy of 3D 7 [102] or investigated computer simulations for semi-automated 3D reconstruction of PISA [103] and found significantly improved accuracy of 3D…”