Real-time monitoring of microwave-promoted organometallic ligand-substitution reactions using in situ Raman spectroscopy

Abstract

An apparatus has been developed for real-time monitoring of organometallic reactions under microwave irradiation using in situ Raman spectroscopy and its application for monitoring ligand substitution reactions of Mo(CO)6 demonstrated.

Organometallic chemistry in the melt phase

“…It has been noted that the wide application of microwave initiation to organometallic chemistry is hampered by some limitations of the technique [95]. These include realtime reaction monitoring using standard techniques (IR, NMR) and the optimization of reaction conditions such as time and temperature.…”

Acid, silver, and solvent-free gold-catalyzed hydrophenoxylation of internal alkynes

“…Although microwave-assisted reactions are legion in organic chemistry, they are rare in organometallic synthesis [15–21]. Our initial report on this chemistry was focused on gold compounds bearing Buchwald-type phosphine ligands such as JohnPhos and t -BuXPhos.…”

Efficient microwave syntheses of the compounds Os3(CO)11L, L=NCMe, py, PPh3

“…In subsequent years, these researchers and others have prepared dozens of metal arene and/or Cp complexes by microwave heating [10][11][12][13][14][15][16]. Several microwave-assisted ligand substitution reactions involving group 6 metal carbonyls have also been reported [17][18][19].…”