Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures

Zhang, Weicheng; Li, Jiandong; Yang, Sihua

doi:10.1016/j.apacoust.2019.06.028

Cited by 15 publications

(5 citation statements)

References 32 publications

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“…Ovarian death is the leading cause of death in women. Therapy has become a hot topic in the research community, especially when it comes to ovarian cancer [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Application of CT Ultrasonography Combined with Microscopic Intraperitoneal Hyperthermic Perfusion Chemotherapy in Postoperative Treatment of Oocyst Carcinoma

Xia

Jin

2022

Scanning

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For the postoperative treatment of oocyte carcinoma, CT and CT ultrasonography combined with microscopic intraperitoneal should be combined with peritoneal heat perfusion chemotherapy. The authors selected 50 patients who received treatment for ovarian cancer from 2017 to 2018 and divided them into two groups (observation group, 30 cases, control group, 20 cases). Cisplatin, associated with peritoneal hyperthermia, led the control group, and we monitored all patients for 1 year and provided clinical trials, lifestyle, and results for both disease group. The experimental results showed that the target reduction rate of the control group was 70%, while that of the control group was only 40%, lower than that of the control group P < 0.05 . The life expectancy of the control group was higher than that of the control group, P < 0.05 . Nausea, vomiting, diarrhea, bone marrow compression, and constipation in the study group were slightly higher than those in the control group (35%), but there was no significant difference between the two groups ( P > 0.05 ). Chemotherapy combined with intraperitoneal infusion of loplatin has no side effects, helps improve survival, and can be used in a variety of clinical trials.

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“…Ovarian death is the leading cause of death in women. Therapy has become a hot topic in the research community, especially when it comes to ovarian cancer [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Application of CT Ultrasonography Combined with Microscopic Intraperitoneal Hyperthermic Perfusion Chemotherapy in Postoperative Treatment of Oocyst Carcinoma

Xia

Jin

2022

Scanning

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“…We performed real-time interleaved photoacoustic and ultrasound imaging [12] , [13] . The sampling rate was 41.67 MHz in photoacoustic imaging and 62.5 MHz in ultrasound imaging.…”

Section: Methodsmentioning

confidence: 99%

Posterior photoacoustic/ultrasound imaging of the periodontal pocket with a compact intraoral transducer

Khazaeinezhad²,

Hariri³

et al. 2022

Photoacoustics

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“…Regarding the limitations of the system, the developed hmPAI system uses a 48 MHz frequency transducer, which is greater than 1 2 the sampling rate of the Verasonics system. To improve image quality and meet the Nyquist criteria, we plan to incorporate an interleaved imaging schematic [40] as the next step. In addition, the hmPAI is constrained to a single imaging plane, and movement of the PA probe for B-or C-scan imaging still relies on the scanning motor.…”

Section: Prospects Of the Developed Hmpai Systemmentioning

confidence: 99%

Assessment of Brain Functional Activity Using a Miniaturized Head-Mounted Scanning Photoacoustic Imaging System in Awake and Freely Moving Rats

et al. 2021

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Understanding the relationship between brain function and natural behavior remains a significant challenge in neuroscience because there are very few convincing imaging/recording tools available for the evaluation of awake and freely moving animals. Here, we employed a miniaturized head-mounted scanning photoacoustic imaging (hmPAI) system to image real-time cortical dynamics. A compact photoacoustic (PA) probe based on four in-house optical fiber pads and a single custom-made 48-MHz focused ultrasound transducer was designed to enable focused dark-field PA imaging, and miniature linear motors were included to enable two-dimensional (2D) scanning. The total dimensions and weight of the proposed hmPAI system are only approximately 50 × 64 × 48 mm and 58.7 g (excluding cables). Our ex vivo phantom experimental tests revealed that a spatial resolution of approximately 0.225 mm could be achieved at a depth of 9 mm. Our in vivo results further revealed that the diameters of cortical vessels draining into the superior sagittal sinus (SSS) could be clearly imaged and continuously observed in both anesthetized rats and awake, freely moving rats. Statistical analysis showed that the full width at half maximum (FWHM) of the PA A-line signals (relative to the blood vessel diameter) was significantly increased in the selected SSS-drained cortical vessels of awake rats (0.58 ± 0.17 mm) compared with those of anesthetized rats (0.31 ± 0.09 mm) (p < 0.01, paired t-test). In addition, the number of pixels in PA B-scan images (relative to the cerebral blood volume (CBV)) was also significantly increased in the selected SSS-drained blood vessels of awake rats (107.66 ± 23.02 pixels) compared with those of anesthetized rats (81.99 ± 21.52 pixels) (p < 0.01, paired t-test). This outcome may result from a more active brain in awake rats than in anesthetized rats, which caused cerebral blood vessels to transport more blood to meet the increased nutrient demand of the tissue, resulting in an obvious increase in blood vessel volume. This hmPAI system was further validated for utility in the brains of awake and freely moving rats, showing that their natural behavior was unimpaired during vascular imaging, thereby providing novel opportunities for studies of behavior, cognition, and preclinical models of brain diseases.

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Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures

Cited by 15 publications

References 32 publications

Application of CT Ultrasonography Combined with Microscopic Intraperitoneal Hyperthermic Perfusion Chemotherapy in Postoperative Treatment of Oocyst Carcinoma

Application of CT Ultrasonography Combined with Microscopic Intraperitoneal Hyperthermic Perfusion Chemotherapy in Postoperative Treatment of Oocyst Carcinoma

Posterior photoacoustic/ultrasound imaging of the periodontal pocket with a compact intraoral transducer

Assessment of Brain Functional Activity Using a Miniaturized Head-Mounted Scanning Photoacoustic Imaging System in Awake and Freely Moving Rats

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