Real time in vivo non-invasive optical imaging using near-infrared fluorescent quantum dots1

Nanoparticles in Biomedical Applications and Their Safety Concerns

“…Coronary vasculature of a rat heart has been imaged with near IR emitting nanoparticles with high sensitivity. (Morgan, English et al 2005) Early detection of cancerous cells is the topic of interest for applications of quantum dots. Multiplexing of quantum dots for the better targeting and sensitivity has been a candidate for this purpose.…”

Semiconductor nanocrystals for biological imaging

“…The surgeon followed the flow of nanocrystals in real time with NIR image guidance, and quickly identified the position of the SLN in a precise and rapid surgical procedure. NIR nanocrystal imaging of blood vessels and beating heart through 1-2 mm of skin and tissues were also reported [39].…”

Synthesis and characterization of self-assembled CdHgTe/gelatin nanospheres as stable near infrared fluorescent probes in vivo

“…They provide several advantages over organic fluorophores for biological imaging, including broad excitation spectra coupled with narrow, tunable emission spectra and high resistance to photobleaching [7]. Lately QDs have been severed as excellent alternatives of traditional dyes in many fluorescence based bioanalytical techniques [8][9][10]. Despite QDs possess many unique optical properties, quite a lot of problems are also noticed for in vivo biological imaging applications.…”