Real-time electromagnetic tracking–based treatment platform for high-dose-rate prostate brachytherapy: Clinical workflows and end-to-end validation

Beaulieu, Luc; Racine, Emmanuel; Han, Dan; Vigneault, Éric; Hsu, I-Chow; Cunha, J. Adam M.

doi:10.1016/j.brachy.2017.04.247

Cited by 33 publications

(31 citation statements)

References 24 publications

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“…Furthermore, one of the most significant challenges for clinical implementation of source position verification using the MP system is the registration of MP and patient coordinate systems. Previous studies have overcome this challenge by using stereoscopic imaging, and electromagnetic tracking technology . Overcoming this challenge will be a focus in future publications.…”

Section: Discussionmentioning

confidence: 99%

HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study

Poder

Cutajar

Guatelli

et al. 2018

J Applied Clin Med Phys

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PurposeThis study aims to assess the accuracy of source position verification during high‐dose rate (HDR) prostate brachytherapy using a novel, in‐house developed two‐dimensional (2D) diode array (the Magic Plate), embedded exactly below the patient within a carbon fiber couch. The effect of tissue inhomogeneities on source localization accuracy is examined.MethodMonte Carlo (MC) simulations of 12 source positions from a HDR prostate brachytherapy treatment were performed using the Geant4 toolkit. An Ir‐192 Flexisource (Isodose Control, Veenendaal, the Netherlands) was simulated inside a voxelized patient geometry, and the dose deposited in each detector of the Magic Plate evaluated. The dose deposited in each detector was then used to localize the source position using a proprietary reconstruction algorithm.ResultsThe accuracy of source position verification using the Magic Plate embedded in the patient couch was found to be affected by the tissue inhomogeneities within the patient, with an average difference of 2.1 ± 0.8 mm (k = 1) between the Magic Plate predicted and known source positions. Recalculation of the simulations with all voxels assigned a density of water improved this verification accuracy to within 1 mm.ConclusionSource position verification using the Magic Plate during a HDR prostate brachytherapy treatment was examined using MC simulations. In a homogenous geometry (water), the Magic Plate was able to localize the source to within 1 mm, however, the verification accuracy was negatively affected by inhomogeneities; this can be corrected for by using density information obtained from CT, making the proposed tool attractive for use as a real‐time in vivo quality assurance (QA) device in HDR brachytherapy for prostate cancer.

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Section: Discussionmentioning

confidence: 99%

HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study

Poder

Cutajar

Guatelli

et al. 2018

J Applied Clin Med Phys

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show abstract

“…Another challenge that is still to be overcome is the registration of the MP900 to the BTPS coordinate system. The accuracy of source tracking can only be as good as the registration between these coordinate systems, and previous publications have incorporated stereoscopic imaging [13,14], or electromagnetic tracking [33] in attempts to perform this registration. However, this issue remains one of the most significant challenges for accurate localisation of the source position and will also be a focus of future publications on experimental results using the MP900 system in combination with gel phantoms.…”

Section: Discussionmentioning

confidence: 99%

A Monte Carlo study on the feasibility of real-time in vivo source tracking during ultrasound based HDR prostate brachytherapy treatments

et al. 2019

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“…The verification of catheter position in HDR prostate brachytherapy via electromagnetic tracking has been proposed by several authors, including Poulin et al (2015) and Beaulieu et al (2018), as an alternative to CT verification of catheter position post-implantation/pre-irradiation. The EM tracking system evaluated by Beaulieu et al (2018) was shown to outperform clinical CT, with a worst-case error of 1.25 mm for tip tracking and 1.91 mm for the overall catheter position for acquisitions of 10 seconds per catheter.…”

Section: Related Workmentioning

confidence: 99%

A simulation study of BrachyShade, a shadow-based internal source tracking system for HDR prostate brachytherapy

Alabd¹,

Safavi-Naeini²,

Wilson³

et al. 2018

Phys. Med. Biol.

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This paper presents a simulation study of BrachyShade, a proposed internal source-tracking system for real time quality assurance in high dose rate prostate brachytherapy. BrachyShade consists of a set of spherical tungsten occluders located above a pixellated silicon photodetector. The source location is estimated by minimising the mean squared error between a parametric model of the shadow image and acquired images of the shadows projected on the detector plane. A novel algorithm is finally employed to correct the systemic error resulting from Compton scattering in the medium. The worst-case error obtained with BrachyShade for a 13.5 ms image acquisition is less than 1.3 mm in the most distant part of the treatment volume, while for 75% of source locations an error of less than 0.42 mm was achieved.

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Real-time electromagnetic tracking–based treatment platform for high-dose-rate prostate brachytherapy: Clinical workflows and end-to-end validation

Cited by 33 publications

References 24 publications

HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study

HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study

A Monte Carlo study on the feasibility of real-time in vivo source tracking during ultrasound based HDR prostate brachytherapy treatments

A simulation study of BrachyShade, a shadow-based internal source tracking system for HDR prostate brachytherapy

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