Real-Time Continuous Glucose Monitoring for People Living With Type 1 Diabetes

Abstract


 Continuous glucose monitoring (CGM) is a method of glucose testing in which a sensor is inserted into the skin and continuously monitors interstitial glucose concentrations. Real-time continuous glucose monitoring (rtCGM) systems automatically measure glucose and display a recent glucose value.
 Evidence suggests that rtCGM may improve hemoglobin A1C and time in range in adults and pediatric patients with type 1 diabetes, but this is uncertain.
 Limited evidence suggests that in people with type 1 diabetes, there is little to no difference between rtCGM and self-monitoring of blood glucose (SMBG) on quality of life, diabetic ketoacidosis, and severe adverse events.
 Safety evidence suggests that rtCGM may decrease severe hypoglycemia in adults and pediatric patients with type 1 diabetes, but this is uncertain.
 rtCGM may be more cost-effective in the long term than SMBG in adults with type 1 diabetes.

Real-Time Continuous Glucose Monitoring for People Living With Type 2 Diabetes

“…Evidence from a cost-effective analysis conducted in Spain suggested that glycemic monitoring with rtCGM was not cost-effective compared to SMBG alone in individuals living with T2D. 18 A recent CADTH report 23 on the clinical effectiveness and cost-effectiveness of rtCGM compared to SMBG in T1D found that rtCGM is favoured over SMBG for glycemic monitoring in adults and pediatric patients. rtCGM was also found to be cost-effective compared to SMBG at a WTP threshold of $50,000 per QALY.…”