Real-life vaccination coverage in Slovak children with rheumatic diseases

Balažiová, Barbora; Kuková, Zuzana; Mišíková, Daša; Novosedlíková, Katarína; Dallos, Tomáš

doi:10.3389/fped.2022.956136

Cited by 4 publications

(7 citation statements)

References 27 publications

(39 reference statements)

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“…The risk of infections, missing treatment, disease flare, and non-achievement of the remission usually are not mentioned as factors, associated with incomplete vaccination. Incomplete vaccination in JIA and pediatric rheumatic disease patients were reported in several previous studies[ 18 , 19 , 30 , 31 , 32 ]. From the medical point of view, the main predictors of incomplete vaccination were polyarticular and systemic JIA categories and immunosuppressive medications[ 30 , 31 , 33 ].…”

Section: Discussionmentioning

confidence: 78%

“…From the medical point of view, the main predictors of incomplete vaccination were polyarticular and systemic JIA categories and immunosuppressive medications[ 30 , 31 , 33 ]. In our previous study, the younger JIA onset age was associated with a higher proportion of omitted vaccines similar to the study of Minden et al [ 18 ], but some authors reported that preschool children had a similar rate of vaccine coverage as healthy peers[ 30 , 32 , 33 ].…”

Section: Discussionmentioning

confidence: 99%

“…Usually, decreased vaccine coverage correlated with patients’ age and teens had more omitted vaccines than preschools[ 18 , 30 , 32 , 33 ]. In our study, the proportion of patients, who received vaccination against pneumococcus was the highest in the IBD subgroup.…”

Section: Discussionmentioning

confidence: 99%

“…There are no contraindications for the administration of inactive or live vaccines in patients who are not receiving immunosuppressive treatment[ 15 , 16 ]. Despite the higher risk of live vaccines in immune-mediated diseases patients there was no strong correlation between the type of omitted vaccines (live or non-live) and disease activity[ 30 , 33 ]. Sometimes patients with pediatric rheumatic diseases might have omitted non-live vaccines[ 30 , 33 ].…”

Section: Discussionmentioning

confidence: 99%

“…Despite the higher risk of live vaccines in immune-mediated diseases patients there was no strong correlation between the type of omitted vaccines (live or non-live) and disease activity[ 30 , 33 ]. Sometimes patients with pediatric rheumatic diseases might have omitted non-live vaccines[ 30 , 33 ]. Contemporary EULAR recommendations for children (2021) and adults (2019) with rheumatic diseases allow using live-attenuated vaccines, especially booster doses of MMR and varicella zoster virus in patients with low-grade immune suppression[ 5 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

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Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data

MAKAROVA¹,

Khabirova²,

Volkova³

et al. 2023

World J Clin Pediatr

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BACKGROUND Patients with immune-mediated diseases, such as juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD) are at increased risk of developing infections, due to disease-related immune dysfunction and applying of immunosuppressive drugs. AIM To evaluate vaccine coverage in patients with IBD and JIA, and compare it with healthy children. METHODS In the cross-sectional study we included the data from a questionnaire survey of 190 Legal representatives of children with JIA ( n = 81), IBD ( n = 51), and healthy children (HC, n = 58). An electronic online questionnaire was created for the survey. RESULTS There were female predominance in JIA patients and younger onset age. Parents of JIA had higher education levels. Employment level and family status were similar in the three studied groups. Patients with JIA and IBD had lower vaccine coverage, without parental rejection of vaccinations in IBD, compare to JIA and healthy controls. The main reason for incomplete vaccination was medical conditions in IBD and JIA. IBD patients had a lower rate of normal vaccine-associated reactions compared to JIA and HC. The encouraging role of physicians for vaccinations was the lowest in JIA patients. IBD patients had more possibilities to check antibodies before immune-suppressive therapy and had more supplementary vaccinations compared to JIA and HC. CONCLUSION JIA and IBD patients had lower vaccine coverage compared to HC. Physicians' encouragement of vaccination and the impossibility of discus about future vaccinations and their outcomes seemed the main factors for patients with immune-mediated diseases, influencing vaccine coverage. Further investigations are required to understand the reasons for incomplete vaccinations and improve vaccine coverage in both groups, especially in rheumatic disease patients. The approaches that stimulate vaccination in healthy children are not always optimal in children with immune-mediated diseases. It is necessary to provide personalized vaccine-encouraging strategies for parents of chronically ill children with the following validation of these technics.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data

MAKAROVA¹,

Khabirova²,

Volkova³

et al. 2023

World J Clin Pediatr

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Influenza vaccine uptake in juvenile idiopathic arthritis: a multi-centre cross-sectional study

Maritsi,

Dasoula,

Ziv

et al. 2024

Eur J Pediatr

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While most countries provide safe and effective influenza vaccines for at-risk groups, influenza vaccine coverage among children with rheumatic diseases remains uncertain. This study investigated influenza vaccination rates in children with juvenile idiopathic arthritis (JIA) during the 2019–2020 season and assessed the knowledge and attitudes of caregivers of children with JIA regarding influenza vaccination. The secondary aims were to identify barriers to vaccination and explore strategies to improve vaccination rates. A multi-centre, cross-sectional anonymous survey was conducted in 7 countries during the 2019–2020 influenza season to assess the uptake history of influenza vaccination. Among 287 participants, only 87 (30%) children with JIA received the influenza vaccine during the 2019–2020 season. Children who were more likely to be vaccinated were those with systemic juvenile idiopathic arthritis (sJIA), a history of previous vaccination and those aware of the vaccination recommendations. Conversely, children who previously experienced adverse vaccine-related events reported the lowest uptake. The primary reason for non-vaccination was lack of awareness about the necessity of influenza vaccination. Conclusion: Despite variations among countries, the uptake of influenza vaccines remains low in children with JIA. Improving awareness among families about the importance of influenza vaccination may increase vaccination rates in children with rheumatic diseases. What is Known:• Rheumatic children are at increased risk for influenza infection due to immunosuppressive therapy and immune dysregulation.• Influenza vaccine is formally recommended to children with rheumatic diseases. What is New:• This multicentre study showed that influenza vaccine uptake rates remain suboptimal among children with Juvenile Idiopathic Arthritis despite formal recommendations.• Factors like previous experience with vaccination and information provided by medical professionals via different ways play essential roles in increasing vaccination rates and can contribute to improved health outcomes for these vulnerable children.

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Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study

Akgün,

Demirkan,

Kavrul Kayaalp

et al. 2023

Postgraduate Medicine

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Real-life vaccination coverage in Slovak children with rheumatic diseases

Cited by 4 publications

References 27 publications

Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data

Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data

Influenza vaccine uptake in juvenile idiopathic arthritis: a multi-centre cross-sectional study

Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study

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