Real Incidence of Diabetes Mellitus in a Coronary Disease Population

Hera, Jesús M. de la; García-Ruiz, José M.; Martínez–Camblor, Pablo; Martín, M.a A.; Tellería, Ana Lucía; Corros, Cecília; Torres, Francisco; Fernández-Cimadevilla, Oliva C.; Alvarez-Pichel, Irene; Capín, Esmeralda; Avanzas, Pablo; Delgado, Elías

doi:10.1016/j.amjcard.2012.10.008

Cited by 18 publications

(14 citation statements)

References 31 publications

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“…This is concordant with the results from previous studies [9,12-14,16,35]. While OGTT is an indispensable tool to detect glucometabolic abnormalities [36,37], FPG is still often used for the diagnosis in daily practice. However, as shown in DECODA (Diabetes Epidemiology: Collaborative Analysis of Diagnostic Criteria in Asia) study [9], it would be inappropriate to use the FPG criteria alone for screening diabetes in Asian populations.…”

Section: Discussionsupporting

confidence: 91%

Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention

Kuramitsu

Yokoi

Domei

et al. 2013

Cardiovasc Diabetol

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BackgroundPost-challenge hyperglycemia (PH) is well-established as one of risk factors for coronary artery disease. However, it remains unclear whether PH affects clinical outcomes in patients with stable angina undergoing percutaneous coronary intervention (PCI).MethodsA total of 828 patients with stable angina undergoing PCI were retrospectively analyzed. Of these, 452 patients with previously diagnosed diabetes mellitus (DM) or fasting plasma glucose (PG) ≥126 mg/dl and HbA1c ≥6.5% were defined as known DM. The remaining 376 patients were divided into the two groups according to 2-h PG: PH (2-h PG ≥140 mg/dl, n=236) and normal glucose tolerance (NGT, 2-h PG <140 mg/dl, n=140). We assessed the rate of major adverse cardiovascular events (MACE), defined as a composite of cardiovascular death, myocardial infarction, stroke, and clinically-driven revascularization.ResultsDuring the median follow-up of 4.3 years, the MACE rate was significantly higher in the DM and PH groups than the NGT group (39.3% vs. 20.7%, P <0.001; 31.4% vs. 20.7%, P=0.044, respectively). Compared with the NGT group, the cumulative incidence of revascularization was significantly higher in the DM group (35.1% vs. 18.5%, P <0.001) and tended to be higher in the PH group (27.1% vs. 18.5%, P=0.067). In the multivariate analysis, known DM (Hazard ratio [HR]: 2.16, 95% confidence interval (CI): 1.49-3.27, P < 0.001), PH (HR: 1.62, 95% CI: 1.07-2.53, P = 0.023), LDL-C >100 mg/dl (HR: 1.62, 95% CI: 1.26 to 2.10, P < 0.001), and previous stroke (HR: 1.47, 95% CI: 1.03-2.04, P = 0.034) were predictors of MACE.ConclusionPH is associated with future cardiovascular events in patients with stable angina undergoing PCI.

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Section: Discussionsupporting

confidence: 91%

Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention

Kuramitsu

Yokoi

Domei

et al. 2013

Cardiovasc Diabetol

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“…Advantage RPG > 11.1 mmol/L routine, always available 1, 27 FBG > 7 mmol/L routine, always available 1, 46 HbA1C > 6.5% widely available, within 24 hours 1, 28 OGTT 2-hr PG ≥ 11.1 mmol/L improves DM detection additionally 26,45 All above provides optimal result in DM detection 36,41,51 RPG -random plasma glucose; FBG -fasting blood glucose; HbA1C -glycated haemoglobin A1c; OGTT -oral glucose tolerance test; PG -plasma glucose. OGTT in a combination with HbA1c provides the additional prognostic information on all-cause mortality, as this identifies a group of high-risk patients, who would remain undetected if using an OGTT, or HbA1c only 38 .…”

Section: Methodsmentioning

confidence: 99%

“…Comparing all three glycemic parameters, FPG, OGTT and HbA1c simultaneously for mortality and CV disease risk reveals that the association is strongest for 2-hour plasma glucose concentration (2hPG) in OGTT 26 . In addition to FPG and HbA1c, OGTT reveals much more cases of DM, both in the general population and CAD 45 . A portion of AMI patients with new-diagnosed AMI by means of OGTT was not negligible 8 .…”

Section: Comparison Of the Most Important Tools To Detect Dm In Ami (mentioning

confidence: 99%

Four varieties of diabetes mellitus in acute myocardial infarction

et al. 2019

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“…Finalmente, debemos señalar que la GBA, la ITG y la HbA1c identifican poblaciones diferentes (18,20,21). También en pacientes tras un evento coronario agudo el TTOG permite detectar un mayor número de pacientes con diabetes que la GB o la HbA1c (22), por lo que cuando los valores de GB y HbA1c no son concluyentes o normales sería recomendable realizar el TTOG en este grupo de pacientes (23).…”

Section: Tabla 2 Estrategias De Cribado De Prediabetes Y Diabetesunclassified

Consenso sobre la detección y el manejo de la prediabetes. Grupo de trabajo de consensos y guías clínicas de la Sociedad Española de Diabetes

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Artola²,

Escalada³

et al. 2014

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Real Incidence of Diabetes Mellitus in a Coronary Disease Population

Cited by 18 publications

References 31 publications

Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention

Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention

Four varieties of diabetes mellitus in acute myocardial infarction

Consenso sobre la detección y el manejo de la prediabetes. Grupo de trabajo de consensos y guías clínicas de la Sociedad Española de Diabetes

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