“…Different approaches have been proposed for FA assays (Bechmann, 1996;Demkiv et al, 2008), among them the most used are chemical and physico-chemical ones, although they are not void of serious drawbacks: low selectivity (chemical methods), necessity in analyte derivatization, costly equipment and trained personal (HPLC, mass-spectrometry, NMR). Recent achievements in the field of FA analysis include enzymatic and biosensor approaches based on the use of bacterial or yeast recombinant formaldehyde dehydrogenase (Ali et al, 2006;Ali et al, 2007;Demkiv, Paryzhak, Gayda, Sibirny, & Gonchar, 2007;Demkiv et al, 2008;Ho & Richards, 1990;Nikitina et al, 2007;Paryzhak, Demkiv, Schuhmann, & Gonchar, 2008) and yeast alcohol oxidase which is able to oxidise FA (Dmytruk et al, 2007;Gonchar, Strzelczyk, Maidan, Bień , & Sibirny, 1998;Sibirny et al, 2008).…”