Reagent Engineering for Group Transfer Biocatalysis
John H. Reed,
Florian P. Seebeck
Abstract:Biocatalysis has become a major driver in the innovation of preparative chemistry. Enzyme discovery, engineering and computational design have matured to reliable strategies in the development of biocatalytic processes. By comparison, substrate engineering has received much less attention. In this Minireview, we highlight the idea that the design of synthetic reagents may be an equally fruitful and complementary approach to develop novel enzyme‐catalysed group transfer chemistry. This Minireview discusses key … Show more
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