Ready-to-use therapeutic food for treatment of marasmus

Briend, André; Lacsala, Radandi; Prudhon, Claudine; Mounier, Béatrice; Grellety, Yvonne; Golden, Michael

doi:10.1016/s0140-6736(99)01078-8

Cited by 142 publications

(149 citation statements)

References 2 publications

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“…All the three formulations were found to be effective in rehabilitation of malnourished albino rats. Ingredients required for the production of these formulations are cheaper than ingredients used to produce Plumpy'Nut (Table 5) [30].…”

Section: Cost Of Production Of the Formulationsmentioning

confidence: 99%

Locally Developed Ready-To-Use-Therapeutic-Food (RUTF) for Management of Malnutrition Using Animal Models

Wamunga¹,

Wamunga²

2017

J Clin Nutr Diet

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Context: The prevalence of protein energy malnutrition in developing countries has reduced globally. However stunting, wasting, and underweight are still unacceptably high. These high levels of protein energy malnutrition are a major cause of high infant and child morbidity, and mortality rates. Community-based therapy for acute childhood malnutrition has been successful in a variety of settings over the last five years. This study therefore sought to develop a readyto-use-therapeutic food using foods that are locally available in Western Kenya.Objective: The objectives of this study were to develop a ready-to-usetherapeutic-food using soybeans; assess consumer acceptability of the locally developed ready-to-use-therapeutic-food, test the effect of formulated products on malnourished animal models, and analyze the cost of local production of the ready-to-use-therapeutic-food.Experimental design: Three formulations were developed using soybeans (Glycine max l. Merr), maize (Zea mays), peanut (Arachis hypogaea), sugar, vegetable oil and mineral mix. Proximate analyses for protein, fat, moisture, carbohydrate and energy were done according to standard AOAC International methods. Hedonic characterization on a 9-point scale was done to determine the liking for colour, flavour, texture, appearance and general acceptability. Preference ranking for consumer acceptability of three formulations was done by 50 University of Eldoret students; 27 female and 23 male students aged 21-30 years.Results: soybeans are a cheaper alternative to dairy products for the production of an acceptable RUTF as recommended by UNICEF standards. This will go a long way in reducing the costs incurred by use of imported ready-to-use-therapeutic food.

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Section: Cost Of Production Of the Formulationsmentioning

confidence: 99%

Locally Developed Ready-To-Use-Therapeutic-Food (RUTF) for Management of Malnutrition Using Animal Models

Wamunga¹,

Wamunga²

2017

J Clin Nutr Diet

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“…1 Reliance on RUTF has a number of operational advantages: it reduces the logistic load for the end user, allows rapid roll-out and access to treatment, permits home-based ambulatory care and is cost-effective. 2,3 One of the most widely used RUTFs in Africa is Plumpy'nut ® (PPN; Nutriset, Malaunay, France; http:// www.nutriset.fr/en/product-range/produit-par-produit/ plumpynut-ready-to-use-therapeutic-food-rutf.html), which is a peanut-based mixture of milk powder, sugar, vegetable oil, minerals and vitamins. It does not require cooking or dilution with water, and is thus practical for use where such resources are limited.…”

Section: Interna Onal Union Against Tuberculosis and Lung Diseasementioning

confidence: 99%

Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh

Ali

Zachariah

Dahmane

et al. 2013

public health action

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with a community-based nutrition programme that has been using PPN for the management of acute malnutrition among children in a slum setting in Dhaka, Bangladesh. Bangladesh has one of the highest prevalence rates of childhood malnutrition in the world: 6,7 almost 46% of children aged <5 years are stunted (low height for age) and 15% are wasted (low weight for height). 8 During the implementation of this nutrition programme, several care givers of children complained of diffi culties in feeding their children with PPN and attributed it to the taste and smell of PPN. The programme also faced challenges in terms of a high lossto-follow-up rate (15-17%) and relatively low nutritional recovery rates (59-65%) compared to those reported in the literature. 9 A relatively long average length of stay in the programme (60-63 days) has also been observed. We are concerned that these fi ndings might be related to the overall acceptability of PPN, which is a key determinant in ensuring favourable outcomes of nutritional rehabilitation. While some studies in Africa have shown that peanut-based RUTF has good acceptability and compliance among severely malnourished children, 10-12 other studies have demonstrated barriers to its use and inadequate compliance, mainly due to sharing within the households. 13,14 There is, however, limited published literature on PPN acceptability in South Asia.In the present study, we assessed the acceptability of PPN among 1) care givers of malnourished children and 2) community health workers (CHWs), in Kamrangirchar slum, Dhaka, Bangladesh. METHODS DesignThis was a cross-sectional semi-structured questionnaire survey. Study setting and study populationThe study was conducted between April and June 2011 in Kamrangirchar, an urban slum setting in Dhaka, Bangladesh, with about 400 000 inhabitants living in an area of 3.1 km 2 . It is not offi cially considered as part of Dhaka City, and all health services are outsourced to non-governmental organisations, who are the main providers.MSF started its nutrition programme for children in May 2010. All services are provided free of charge . It is to be noted that 47% of children needed encouragement or were forced to eat PPN, while 5% completely rejected it after 3 weeks. Of the 29 CHWs interviewed, 48% were dissatisfied with PPN's taste and consistency, and 55% with its smell. However, 91% of the care givers and all CHWs still perceived a therapeutic benefit of PPN for malnourished children. Conclusion: Despite a therapeutic benefit, only 4 in 10 care givers perceived PPN as being acceptable as a food product, which is of concern. Interna onal Union Against Tuberculosis and Lung Disease

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“…RUTF has been used as a substitute to therapeutic diets (F-75/F-100) in African settings and these foods have been found to be effective for community-based care of children, with SAM in studies conducted in Africa (Briend et al, 1999;Dossou et al, 2003). RUTF is a mixture of milk powder, vegetable oil, sugar, peanut butter, and powdered vitamins and minerals, and is energy-dense food providing 5.5Kcal/g.…”

Section: Community-based Management Of Severe Acute Malnutritionmentioning

confidence: 99%

Management of SAM and MAM

Kulkarni¹

2016

Proceedings of the Indian National Science Academy

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Moderate acute malnutrition (MAM) i.e. weight for height z-score (WHZ) between -2 and -3 and severe acute malnutrition (SAM) i.e. WHZ score <-3 in children have serious consequences, contributing to increased morbidity and mortality, and require targeted interventions. Children with SAM and associated medical complications are at high risk of mortality and need facility-based management. The paper describes the guidelines by World Health Organization (WHO) and Indian Academy of Paediatrics (IAP) for inpatient and community based management of SAM. Experience of nutrition rehabilitation at National Institute of Nutrition, Hyderabad, has shown that it is possible to treat SAM children using local foods. A few studies that have also assessed the effectiveness of the Ready to Use Therapeutic Foods (RUTF) for the management of SAM in Indian settings have shown low mortality and high cure rates in non-defaulting children. More evidence on the costeffectiveness and sustainability of this intervention is, however, required. The prevalence of MAM is much larger than that of SAM and children with MAM are also vulnerable to enhanced risk of mortality and morbidity. WHO has recommended that children with MAM should receive nutrient-dense foods to meet their extra needs for weight gain, height gain and functional recovery; however, there is no definitive consensus on the most effective way to treat children with MAM. Finally, prevention of acute malnutrition requires a far wider spectrum of interventions beyond clinical management and need to focus on multi-sectoral actions.

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Ready-to-use therapeutic food for treatment of marasmus

Cited by 142 publications

References 2 publications

Locally Developed Ready-To-Use-Therapeutic-Food (RUTF) for Management of Malnutrition Using Animal Models

Locally Developed Ready-To-Use-Therapeutic-Food (RUTF) for Management of Malnutrition Using Animal Models

Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh

Management of SAM and MAM

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