Readmission to an Intensive Care Unit After Lung Transplantation: Experience of a Single Center

Levine, Deborah J.; Alfredo, Luis; Sako, Edward Y.; Levine, Stephanie M.

doi:10.1378/chest.128.4.1951

Cited by 17 publications

(2 citation statements)

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“…[ 3 – 4 ] Another Chicago hospital reported both cocaine and heroin use as a risk for intubation in asthma. [ 5 ] There are few if any published data on the linkage between heroin use and asthma exacerbations of lesser severity, not requiring ICU admission.…”

Section: Introductionmentioning

confidence: 99%

Medical Diagnoses Associated with Substance Dependence among Inpatients at a Large Urban Hospital

et al. 2015

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BackgroundThere are limited data on reasons for hospital admission among patients dependent on substances other than alcohol. We compared primary discharge diagnoses for heroin- or cocaine-dependent patients to non-dependent patients.Material and MethodsWe evaluated a cohort of patients admitted to a general medicine service at a public teaching hospital during July 2005-June 2008. Through bedside interviews, we identified patients who had substance-use disorders. We categorized patients by substance used, route of administration, and dependent or non-dependent use. We grouped diagnostic codes (i.e., ICD-9) using Healthcare Utilization Project categories. We excluded HIV-infected patients.ResultsOf 11,397 patients, 341 (3.0%) were dependent on inhalational heroin, 260 (2.3%) on non-injection cocaine, and 106 (0.9%) on injection heroin. Compared to non-dependent patients, inhalational heroin-dependent patients were over three-fold more likely to have been admitted for respiratory diseases (28% vs. 8%, p<0.01); this association was strongest for asthma exacerbation (OR=7.0; 95% CI, 4.7 to 70.4, p<0.01). Of the 225 admissions for an asthma exacerbation, 44 (19.6%) had co-occurrent heroin-dependence. The most frequent diagnostic category among cocaine-dependent patients was circulatory, which was similar to non-dependent patients (22% vs. 21%, p=0.92).DiscussionThere is a strong association between heroin dependence and hospital admission for an asthma exacerbation. Provision of specialized substance-use treatment for inhalational heroin users will be necessary to reduce the frequency of exacerbations and repeat hospital admissions.

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Section: Introductionmentioning

confidence: 99%

Medical Diagnoses Associated with Substance Dependence among Inpatients at a Large Urban Hospital

et al. 2015

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“…2005 found that cocaine and heroin abuse increased the rate of intubations and hospital utilization in patients with acute asthma exacerbation. [11]…”

Section: Introductionmentioning

confidence: 99%

Etiological characterization of acute poisonings in the emergency department

Khlifi

Zun

Johnson

et al. 2009

J Emerg Trauma Shock

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Introduction:An investigation of emergency department (ED) poisonings was conducted to characterize poisoning demographics and evaluate correlations with select co-morbidities.Methods:The study population evaluated consisted of 649 poisoning cases admitted between 2004 and 2007 to an inner-city, level 1 emergency department.Results:Ethnicity, age, and gender had a substantial impact on the population distribution as poisoning cases were predominantly African Americans (79.9%) between 36 and 45 years old with a 1:3 male to female ratio. Intentional illicit drug overdose was the most prevalent cause of poisoning, heroin being the most frequent substance found in 35.4% (n = 230) of cases, followed by cocaine overdose at 31.7% (n = 206), concomitant heroin and cocaine overdose at 4.3% (n = 28), multiple drug poisoning at 5.5% (n = 36), and antidepressant/antipsychotic poisoning at 6% (n = 39). Significant correlations were found between heroin poisoning and asthma (F = 20.29, DF = 1, P = 0.0001), cocaine poisoning and hypertension (F = 33.34, DF = 1, P = 0.0001), and cocaine poisoning and cardiovascular disease (F = 35.34, DF = 1, P = 0.0001). A change in the pattern of illicit drug use from injection to inhalation was detected and the resulting increase of inhalation and insufflation of illicit substances may partially explain the correlation found between heroin use and asthma.Conclusions:These results provide supporting evidence that deliberate poisoning with illicit drugs remains a serious healthcare issue that significantly aggravates co-morbidities and raises treatment costs by increasing both the rate of hospitalization and hospital length of stay.

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Life-threatening Asthma: Focus on Lung Protection

Martinez

Ferguson

2009

Intensive Care Medicine

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Readmission to an Intensive Care Unit After Lung Transplantation: Experience of a Single Center

Cited by 17 publications

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Medical Diagnoses Associated with Substance Dependence among Inpatients at a Large Urban Hospital

Medical Diagnoses Associated with Substance Dependence among Inpatients at a Large Urban Hospital

Etiological characterization of acute poisonings in the emergency department

Life-threatening Asthma: Focus on Lung Protection

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