Reactivite de ( 1-H )-diazepines-1,2. Synthese D'homodiazepines.

Taurand, G.; Streith, Jacques

doi:10.1016/s0040-4039(01)94103-6

Cited by 11 publications

(2 citation statements)

References 11 publications

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“…Based on our previous experience, we selected a modification of pyrazolo [3,4-d] [1,2]diazepin-8-one. Of all the known publications [6][7][8][9][10][11][12][13] , the simplest and most convenient way to obtain it is the hydrazinolysis of 3,5-diphenylpyrano [3,4-c]pyrazole-8(1H)-one [11] . This approach is characterized by the simplicity of the reaction scheme, the use of inexpensive reagents, and allows a broad modification of the initial molecule.…”

Section: Resultsmentioning

confidence: 99%

A little about Pyrazolo[3,4-d][1,2]diazepine: simple sustainable synthesis, NMR identification and prototropic equilibrium

Bohza

Bohdan

Stepanova

et al. 2022

Preprint

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A simple and sustainable method for the synthesis of pyrazolo [3,4-d] [1,2] diazepin-8-one, the heterocyclic isoster of 2,3-benzodiazepine, has been developed. It was found that the use of acids to cyclization of the pyrazolopyrone hydrazinolysis product leads to the formation of a condensed pyridine ring instead of 1,2-diazepine. Pyrazolodiazepinone in acidic medium also dramatically contracts the seven-membered cycle. The structure of this compound is proved by the hmbc and hsqc 2D NMR heteronuclear correlation in deuterated dimethyl sulfoxide solution in dynamic. Was studied the transformation of its tautomers. It was found that the problem for the pyrazolo [3,4-d] [1,2] diazepin-8-one molecule identification is caused by prototropic isomerization of the pyrazole ring.

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Section: Resultsmentioning

confidence: 99%

A little about Pyrazolo[3,4-d][1,2]diazepine: simple sustainable synthesis, NMR identification and prototropic equilibrium

Bohza

Bohdan

Stepanova

et al. 2022

Preprint

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“…The nitrene from the triazole (160) [II Irradiation of the 1,4-diphenylphthalazine derivative (162) gave o-dibenzoylbenzene (96), and of the benzocinnoline derivative (163) gave benzocinnoline and the nitrene (51). Quinazolines 164 in this reaction gave the pyridine and form an ethylenimine (170); loss of hydrogen halide from 170 leads to an aziridine (171) which converts the pyridine imine into the pyridotriazine (172) (70).…”

Section: Rc6h4ch=nn(ch3)3mentioning

confidence: 99%

Chemistry of Aminimides

Wawzonek¹

1980

Ind. Eng. Chem. Prod. Res. Dev.

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The period 1972-1979 saw considerable activity in research of the chemistry and utilization of aminimides. Studies have extended investigation to aminimides in which the acyl group is derived from imino acids, cyanuric acid, phosphonic acids, and picric acid and to vinylogues of aminimides. Work continued with aminimides derived from nitrogen heterocycles and their conversion to diazepines and bridged nitrogen bicyclic compounds. Commercial utilization of aminimides based on 1,1dimethylhydrazine has been hampered in this country by the loss of the sole commercial source of this compound.

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