Reactive Oxygen Species-Responsive Sequentially Targeted AIE Fluorescent Probe for Precisely Identifying the Atherosclerotic Plaques
Jie Liu,
Zhigui He,
Yuan Zhong
et al.
Abstract:The formation of atherosclerosis is the root cause of
various cardiovascular
diseases (CVDs). Therefore, effective CVD interventions call for precise
identification of the plaques to aid in clinical treatment of such
diseases. Herein, a reactive oxygen species (ROS)-responsive sequentially
targeted fluorescent probe is developed for atherosclerotic plaque
recognition. An aggregation-induced emission active fluorophore is
linked to maleimide (polyethylene glycol) hydroxyl with a ROS-responsive
cleavable bond, w… Show more
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