Reactive oxygen species and plant resistance to fungal pathogens

Lehmann, Silke; Serrano, Mario; L’Haridon, Floriane; Tjamos, Sotiriοs E.; Métraux, Jean‐Pierre

doi:10.1016/j.phytochem.2014.08.027

Cited by 258 publications

(177 citation statements)

References 145 publications

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“…Another possible mechanism is the redox modification of CP by ROS. ROS is likely involved in redox signaling during plant defense, mainly through regulation of protein activities via glutathionylation of protein Cys thiol residues (Lehmann et al, 2015). Both subunits of human CP are glutathionylated during oxidative stress (Lind et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

Capping Protein Modulates Actin Remodeling in Response to Reactive Oxygen Species during Plant Innate Immunity

Cao

Staiger

2016

Plant Physiol.

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Plants perceive microbe-associated molecular patterns and damage-associated molecular patterns to activate innate immune signaling events, such as bursts of reactive oxygen species (ROS). The actin cytoskeleton remodels during the first 5 min of innate immune signaling in Arabidopsis (Arabidopsis thaliana) epidermal cells; however, the immune signals that impinge on actin cytoskeleton and its response regulators remain largely unknown. Here, we demonstrate that rapid actin remodeling upon elicitation with diverse microbe-associated molecular patterns and damage-associated molecular patterns represent a conserved plant immune response. Actin remodeling requires ROS generated by the defense-associated NADPH oxidase, RBOHD. Moreover, perception of flg22 by its cognate receptor complex triggers actin remodeling through the activation of RBOHDdependent ROS production. Our genetic studies reveal that the ubiquitous heterodimeric capping protein transduces ROS signaling to the actin cytoskeleton during innate immunity. Additionally, we uncover a negative feedback loop between actin remodeling and flg22-induced ROS production.

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Section: Discussionmentioning

confidence: 99%

Capping Protein Modulates Actin Remodeling in Response to Reactive Oxygen Species during Plant Innate Immunity

Cao

Staiger

2016

Plant Physiol.

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“…While reactive oxygen species (ROS)-mediated defense responses are well documented (Dietz, 2003;Torres, 2010;Mittler et al, 2011;O'Brien et al, 2012;Frederickson Matika and Loake, 2014;Lehmann et al, 2015;Trapet et al, 2015), the precise role of NAD in ROSrelated plant immunity remains poorly understood. ROS bursts contribute to basal defense responses after the perception of pathogen-associated molecular patterns (PAMPs), which are conserved molecules for a whole class of microbes, or via damage-associated molecular patterns (DAMPs), which are signals of cell disintegration (Heil and Land, 2014;Macho and Zipfel, 2014).…”

mentioning

confidence: 99%

NAD Acts as an Integral Regulator of Multiple Defense Layers

et al. 2016

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(J.T.).Pyridine nucleotides, such as NAD, are crucial redox carriers and have emerged as important signaling molecules in stress responses. Previously, we have demonstrated in Arabidopsis (Arabidopsis thaliana) that the inducible NAD-overproducing nadC lines are more resistant to an avirulent strain of Pseudomonas syringae pv tomato (Pst-AvrRpm1), which was associated with salicylic acid-dependent defense. Here, we have further characterized the NAD-dependent immune response in Arabidopsis. Quinolinate-induced stimulation of intracellular NAD in transgenic nadC plants enhanced resistance against a diverse range of (a)virulent pathogens, including Pst-AvrRpt2, Dickeya dadantii, and Botrytis cinerea. Characterization of the redox status demonstrated that elevated NAD levels induce reactive oxygen species (ROS) production and the expression of redox marker genes of the cytosol and mitochondrion. Using pharmacological and reverse genetics approaches, we show that NAD-induced ROS production functions independently of NADPH oxidase activity and light metabolism but depends on mitochondrial respiration, which was increased at higher NAD. We further demonstrate that NAD primes pathogen-induced callose deposition and cell death. Mass spectrometry analysis reveals that NAD simultaneously induces different defense hormones and that the NAD-induced metabolic profiles are similar to those of defense-expressing plants after treatment with pathogen-associated molecular patterns. We thus conclude that NAD triggers metabolic profiles rather similar to that of pathogen-associated molecular patterns and discuss how signaling cross talk between defense hormones, ROS, and NAD explains the observed resistance to pathogens.

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“…Generally, the cell wall of host cells is strengthened with the start of pathogenesis gene transcription. In the infection by pathogen, the active forms of oxygen are formed causing the death of infected cells [24].…”

Section: Events Of Infected Plant Cell After Recognition With Bacteriamentioning

confidence: 99%

Molecular events of pathogenic agents invasion of host cells: toward induced resistance

El-Ansary¹

2017

JCLM

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Reactive oxygen species and plant resistance to fungal pathogens

Cited by 258 publications

References 145 publications

Capping Protein Modulates Actin Remodeling in Response to Reactive Oxygen Species during Plant Innate Immunity

Capping Protein Modulates Actin Remodeling in Response to Reactive Oxygen Species during Plant Innate Immunity

NAD Acts as an Integral Regulator of Multiple Defense Layers

Molecular events of pathogenic agents invasion of host cells: toward induced resistance

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