Reactive lesions of the gingiva

Abstract

Abstract. A total of 279 cases of reactive lesions of the gingiva have been subdivided into three groups: pyogenic granuloma/gingival fibromatoid lesions, peripheral giant cell granuloma and peripheral ossifying fibroma. Age, sex and and site distribution are similar for pyogenic granuloma/ gingival fibromatoid lesions and peripheral giant cell granuloma; namely, comparable bimodal age peaks occur, women are affected more often, and a predilection exists for the anterior segment of the dental arch. Although peripheral ossifying fibromas also have the same sex and site predilection, incidence occurs as a single age peak in the second decade with a continuous decline thereafter. Clinical and histopathologic features invite speculation that all three lesions represent varied histologic responses to irritation.

Peripheral Ossifying Fibroma Secondary to Pulpo-Periodontal Irritation

“…Oral hygiene maintenance instructions were also given. A recurrence rate of 20% has been reported, mainly due to incomplete removal of the lesion and/or persistence of aetiological factors [9]. However, there has not been any recurrence of the lesion, two years post operatively.…”

Peripheral ossifying fibroma

“…The etiology of the peripheral ossifying fibroma is unknown, although some authors have suggested that the lesion is associated with inflammatory hyperplasia of the periodontal ligament [4,8]. Others speculate about a possible hormonal influence since prepubertal patients are rarely affected and the disease incidence falls significantly after the third decade of life [8].…”

“…Histologically, the lesion consists of fibrous proliferation associated with formation of mineralized tissue, which can resemble both cement and dystrophic calcification. When former is observed, the lesion is called peripheral cemento ossifying fibroma [4,5]. The objective of the present article is to report a case of POF occurring in the maxillary anterior region of a 13 year old girl.…”

“…Although this lesion is thought to be relatively common, it accounts for less than 1% of all oral biopsies performed. The lesion usually doesn't exceed 2.0 cm and involves predominantly the anterior region of the mandible affects more commonly females and it is more frequently found during the second decade of life [2][3][4][5][6][7][8].…”

“…Peripheral ossifying fibroma (POF) is a reactive lesion characterized by the growth of non-neoplastic mass in the gingiva [2][3][4][5][6]. Its color may resemble that of a normal mucosa or may be slightly reddish and its surface may be either intact or ulcerated [2].…”