Reactive changes of disc space and foreign body granuloma due to bone wax in lumbar spine

Özdemir, Nail; Gelal, Mustafa Fazıl; Minoğlu, Mustafa; Çelìk, Levent

doi:10.4103/0028-3886.55606

Cited by 18 publications

(11 citation statements)

References 15 publications

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“…Bone wax granulomas have been reported in mastoid tissue, the sternotomy site, the lumbar disc surgical site, the cerebellopontine angle, the subarachnoid space near the medulla oblongata, the femoral neck osteoplasty site, orbits, cranial defects, after tibial tubercle elevation surgery and after foot surgery [11]. In an anatomico-pathological study of 18 cadavers, it was reported that bone wax induces chronic inflammation and granuloma formation in the sternum postoperatively [12, 13]. Interestingly, the computed tomographic (CT) examination which is usually decided as the first diagnostic choice for the management of a patient with sternal dehiscence was unable to detect bone wax-related granuloma [12, 13].…”

Section: Discussionmentioning

confidence: 99%

“…In an anatomico-pathological study of 18 cadavers, it was reported that bone wax induces chronic inflammation and granuloma formation in the sternum postoperatively [12, 13]. Interestingly, the computed tomographic (CT) examination which is usually decided as the first diagnostic choice for the management of a patient with sternal dehiscence was unable to detect bone wax-related granuloma [12, 13]. Thus magnetic resonance imaging (MRI) is recommended for evaluation of a complicated sternal wound.…”

Section: Discussionmentioning

confidence: 99%

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CARDIAC SURGERY Use of bone wax is related to increased postoperative sternal dehiscence

Alhan

Aritürk

Şenay

et al. 2014

kitp

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AimTo investigate the relation between use of bone wax and postoperative sternal dehiscence after cardiac surgery.Material and methodsFive thousnad three hundred and eighteen consecutive patients who underwent cardiac surgery between 1999 and 2009 were evaluated prospectively. Perioperative use of bone wax, perioperative data and outcome parameters were recorded. Multivariate logistic regression analysis was performed to define independent risk factors for postoperative sternal dehiscence.ResultsBone wax was used in a total of 1151 (21%) patients. Postoperative sternal dehiscence was detected in 88 (1.6%) patients. The postoperative sternal dehiscence rate was 1.4% in patients without bone wax and 2.5% in patients with bone wax (p = 0.001). The rate of bone wax use was 36.4% in patients with sternal dehiscence and 21.4% in patients without sternal dehiscence (p < 0.001). Independent risk factors for postoperative sternal dehiscence were defined as: age > 70 (OR = 1.9, 95% CI: 1.2-3.1, p = 0.005), chronic obstructive lung disease (OR = 2.4, 95% CI: 1.5-3.9, p < 0.001), use of bone wax (OR = 1.6, 95% CI: 1.03-2.5, p = 0.03), nonelective operation (OR = 2, 95% CI: 1.1-3.4, p = 0.009), and body mass index > 30 (OR = 2.2, 95% CI: 1.4-3.5, p < 0.001).ConclusionsOur findings suggest that use of bone wax may be associated with increased postoperative sternal dehiscence after cardiac surgery. Thus liberal use of bone wax should be restricted.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

CARDIAC SURGERY Use of bone wax is related to increased postoperative sternal dehiscence

Alhan

Aritürk

Şenay

et al. 2014

kitp

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“…It is well known that bone wax has deleterious consequences in bone healing and may contribute to postoperative complications [11][12][13][14][15][16][17] . However, bone wax has been used in craniofacial surgery because of its efficiency and low cost.…”

Section: Discussionmentioning

confidence: 99%

Histological and radiological changes in cranial bone in the presence of bone wax

Raposo-Amaral¹,

Almeida²,

Paschoal

et al. 2011

Acta Cir. Bras.

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. Responsible for conception and design of the study. ABSTRACT Purpose:To quantify the amount of bone formation in the calvarial region of Wistar rats after craniotomy using bone wax as a haemostatic agent. Methods: Surgery to produce bilateral, symmetric, full-thickness cranial defects (area: 18 mm 2 ) was performed in eight animals. The right side of the cranium remained open and the edges of the left side osseous defect was covered with bone wax. Calvaria were imaged immediately after surgery and 12 weeks postoperatively by computerized tomography. The areas of the bone defects were measured in three-dimensional images using Magics 13.0 (Materialise-Belgic, software CAD). Results: The average amount of bone formation on the left and right side respectively was 4.85 mm 2 and 8.16 mm 2 . Statistically significant differences between the amount of bone formation on the left and right sides were seen. Conclusion: Bone wax significantly diminishes the rate of bone formation in calvarial defects in a rat model.

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“…Besides, cases such as infection as well as damages to surrounding tissues are also reported . Therefore the application of bone wax in bone surgery is under controversy currently . Research interests are moved to searching its potential alternatives.…”

Section: Introductionmentioning

confidence: 99%

Using calcium sulfate cement—Hydroxypropyl methyl cellulose/sodium alginate composites as substitutes of bone wax

Zhou

Yang

et al. 2017

Int J Applied Ceramic Tech

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Development of alternatives of bone wax to stop blood transfusion occurred in cancellous bone injury is highly deserved clinically. An ideal candidate is supposed to be not only biodegradable, biocompatible, malleable, and cost-effective, but also have comparable mechanical strength to cancellous bone. In the present work, calcium sulfate cement (CSC) based composites modified with hydroxypropyl methyl cellulose (HPMC) or sodium alginate (SA) were prepared. In brief, CSC was combined with 2, 4, 6 wt.% of HPMC or SA, respectively, followed by setting behavior evaluation, compressive strength and degradation testing, XRD, and SEM characterizations, as well as blood clotting induction study.Both additives improved the hemostatic performance of CSC, but CSC with 2% wt. SA exhibited the optimum setting time, mechanical strength, stability, and blood clotting ability. These results reveal the feasibility of using CSC-SA based composite as a substitute for bone wax.

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Reactive changes of disc space and foreign body granuloma due to bone wax in lumbar spine

Cited by 18 publications

References 15 publications

CARDIAC SURGERY Use of bone wax is related to increased postoperative sternal dehiscence

CARDIAC SURGERY Use of bone wax is related to increased postoperative sternal dehiscence

Histological and radiological changes in cranial bone in the presence of bone wax

Using calcium sulfate cement—Hydroxypropyl methyl cellulose/sodium alginate composites as substitutes of bone wax

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