Reactions of Vanillin and its Derived Compounds. I. The Reaction of Vanillin with Silver Oxide¹

New vanillin-derived diepoxy monomers for the synthesis of biobased thermosets

“…Here, it was synthesized from vanillin by a mild, efficient and environmentally friendly Dakin reaction. Vanillic acid can either be obtained directly from lignin depolymerization [28] or from vanillin oxidation [29]. Vanillyl alcohol can also be prepared from vanillin, by reducing it.…”

A note on the synthesis of veratric acid*

“…Pearl (11) has recently reported that vanillin is oxidized in substantially quantitative yields to vanillic acid by means of alkali and one-half mole of silver oxide, a reaction which he later showed (12) to be generally applicable for the preparation of ortho and para hydroxy substituted aromatic acids from the corresponding aldehydes. His method has been applied with good results to the preparation of veratric acid.…”

Catabolism of 4-hydroxybenzoate in proceeds through initial oxidative decarboxylation by a FAD-dependent 4-hydroxybenzoate 1-hydroxylase

“…2-Fluoro-4-hydroxybenzoate was prepared from 2-fluoro-4-hydroxybenzaldehyde by oxidation with silver oxide [22]. 2-Fluoro-4-hydroxybenzaldehyde was prepared from 3-fluorophenol by the Reimer-Tiemann reaction [23].…”