Reactions of the fac-[Re(CO)3]+ and [ReO]3+ moieties with substituted benzothiazoles

Tuning the Reactivity in Classic Low-Spin d6 Rhenium(I) Tricarbonyl Radiopharmaceutical Synthon by Selective Bidentate Ligand Variation (L,L′-Bid; L,L′= N,N′, N,O, and O,O′ Donor Atom Sets) in fac-[Re(CO)3(L,L′-Bid)(MeOH)]n Complexes

“…The application thereof for the treatment of cancer was spearheaded by and has to be credited to a large extent to Alberto et al − Characteristics which render complexes of the type fac -[M­(CO) 3 (H 2 O) 3 ] + so attractive for application in nuclear medicine are the inert fac -[M­(CO) 3 ] + core, from classic crystal field considerations, and the relative labile water molecules bound to it. It is no wonder then that several promising compounds have been synthesized in the past few years by employing these tricarbonyl synthons by linking it to biomolecules as target director systems. − …”

The reaction of a potentially N2S-donor bis[benzo(thiazole/imidazole)] with the fac-[Re(CO)3]+ and cis-[ReO2]+ cores

“…The focus is mainly on the + I (d 6 ) and + V (d 2 ) oxidation states of the metal, since they can be easily reached from the reduction of perrhenate [2].…”

“…We have previously used the related 2-(2-aminophenyl)benzothiazole (Habt) and 2-(2-hydroxyphenyl) benzothiazole (Hhpd) as bidentate ligands in their reactions with [Re(CO) 5 Br] and trans-[ReOBr 3 (PPh 3 ) 2 ] respectively [6]. In the respective products fac- In this account the reactions of the potentially tridentate ligands bis(benzothiazol-2-ylethyl) sulfide (bts) and its benzimidazole equivalent (btn, Scheme 1) with [Re(CO) 5 Br] and cis-[ReO 2 I(PPh 3 ) 2 ] are reported.…”